Current bachelor students

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Tereza Adámková

Bachelor training

Status: Ongoing 2017
Synthesis of benzoxazol-pyrimidines with with potent anti-TB properties
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Romana Bajerová

Bachelor training

Status: Ongoing 2016
Modification of Polyphenols
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Zuzana Balová

Bachelor training

Status: Ongoing 2016
Synthesis of S-imidazopyridines with potential dual PDE4 / PDE7 activity
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Adam Beňko

Bachelor training

Supervisor:
Status: Ongoing 2016
Choline derivatives as potential cancer diagnostics and therapeutics
The study is focused into evaluation of in vitro and in vivo properties of de novo prepared choline derivatives in order to determine their potential therapeutical and/or diagnostic value in cancer patients.
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Daniel Boyko

Bachelor training

Supervisor:
Status: Ongoing 2017
Targeted metabolomics of transgenic mice suffering from LPS-induced neuroinflammation
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Karolína Burešová

Bachelor training

Status: Ongoing 2013
Biomarkers associated with proliferation, survival, and cell death in breast cancer: possible application in clinical medicine
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Alexandra Dolníková

Bachelor training

Status: Ongoing 2016
Cytogenetic changes in lung cancer patients
Bachelor’s thesis is focused on cytogenetic changes in lung cancer patients. Student will prepare a probe to investigate copy number of EGFR (located on chromosome 7) or the presence of inversion in ROS1 (located on chromosome 6) and ALK (located on chromosome 2). Status of these genes will be investigated by FISH method. Also another change will be detected – presence of HPV in lung cancer tissues using PCR.
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Kateřina Hanáková

Bachelor training

Status: Ongoing 2017
Enzymatic Cleavage of cephalosporin derivatives
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Vladimír Horka

Bachelor training

Supervisor:
Status: Ongoing 2016
Conjugates of betulin prepared by cycloaddition reactions
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Kateřina Hošková

Bachelor training

Status: Ongoing 2016
Chromosomal aberations analysis in children with autistic spectrum disorders
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Markéta Chlubnová

Bachelor training

Supervisor:
Status: Ongoing 2016
The anticancer activity mediated by new A3 receptor agonists
The aim of the thesis is to summarize current knowledge about the role of A3 adenosine receptor in cancer development and anti-cancer effects of newly characterized A3 agonists. The experimental part of thesis is focused on whether or not the anti-cancer effects of A3 agonists described in literature are mediated by direct modulation of A3 receptor.
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Nikola Jakubcová

Bachelor training

Supervisor:
Status: Ongoing 2016
Preparation of substituted thiazole derivatives of ursolic acid
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Jiří Jančík

Bachelor training

Supervisor:
Status: Ongoing 2016
Preparation of new serotonin receptor ligands
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Kateřina Ječmeňová

Bachelor training

Supervisor:
Status: Ongoing 2016
Spectroscopic characteristics used drugs and their use in the identification of molecular targets
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Silvie Kaločová

Bachelor training

Supervisor:
Status: Ongoing 2016
Laser microdissection and analysis of selected cell types of prostate cancer
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Petra Kremserová

Bachelor training

Supervisor:
Status: Ongoing 2016
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Kateřina Kubáňová

Bachelor training

Supervisor:
Status: Ongoing 2016
Validation of HPV68 genotypization in cervical smears
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Tereza Lausová

Bachelor training

Supervisor:
Status: Ongoing 2016
MiRNA and mRNA Profiling in Meningiomas
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Michaela Mašová

Bachelor training

Supervisor:
Status: Ongoing 2016
Meaning HSD17B1 gene amplification in breast cancer
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Martin Mičic

Bachelor training

Status: Ongoing 2016
Structure optimization of iron chelators
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Tereza Michalčíková

Bachelor training

Supervisor:
Status: Ongoing 2016
Labelled peptides for multimodal in vivo imaging of cancer
The aim of this bachelor thesis is preclinical testing of two peptide bioconjugates as potential agents with nuclear and optical signaling for oncological applications. The main goal of the study is to determine in vitro characteristics of studied bioconjugates, their in vivo behaviour in tumor mice and to evaluate their potential for diagnosis of cancer using imaging techniques
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Jan Moštěk

Bachelor training

Supervisor:
Status: Ongoing 2017
Base excision repairs
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Petr Nickl

Bachelor training

Status: Ongoing 2015
Specific genome editing by nucleases
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Denisa Olejníková

Bachelor training

Supervisor:
Status: Ongoing 2016
Synthesis of new lupane derivatives modified at position 20 or 30
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Renáta Páníková

Bachelor training

Status: Ongoing 2016
Synthesis of derivatives of imidazopyridine
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Oliver Pešát

Bachelor training

Status: Ongoing 2016
Standardization of automatic FISH method in cancer patients
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Sebastian Reichel

Bachelor training

Status: Ongoing 2014 to 2017
Detection of circulating tumor cells
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Andrej Soos

Bachelor training

Supervisor:
Status: Ongoing 2016
Crosstalk between the ubiquitin proteasome system and genome integrity
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Vojtěch Synek

Bachelor training

Supervisor:
Status: Ongoing 2014 to 2017
Cytotoxicity tests for high-throughput drug discovery
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Ondřej Šanovec

Bachelor training

Supervisor:
Status: Ongoing 2017
DNA damage response
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Samuel Školuda

Bachelor training

Supervisor:
Status: Ongoing 2016
Cellular response to stress in cancer models
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Petra Šťastná

Bachelor training

Supervisor:
Status: Ongoing 2017
Metabolism study of nilotinib by mass spectrometry
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Petra Švarcová

Bachelor training

Supervisor:
Status: Ongoing 2014 to 2017
Predictive and Prognostic Biomarkers of gene expression
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Zdeňka Trhlíková

Bachelor training

Supervisor:
Status: Ongoing 2013 to 2016
Preparation of heterocyclic triterpenes
The main aim is to prepare a small set of new heterocyclic triterpenoid derivatives using condensation reactions of triterpenoid precursors with ethylene diamine, urea derivatives, hydrazine and other small molecules. Our previous research of triterpenoid heterocycles resulted in several compounds with high in vitro cytotoxic activity and this work should further explore this topic. New derivatives prepared within this work will be tested for their in vivo cytotoxic activity and the best candidates will be selected for more biological examinations.
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Petra Voglová

Bachelor training

Status: Ongoing 2017
Synthesis of benzoxazol-triazoles with potent anti-TB properties
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Tereza Voltemarová

Bachelor training

Supervisor:
Status: Ongoing 2017
DNA damage response
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Barbora Vránová

Bachelor training

Supervisor:
Status: Ongoing 2016
Preparation of betulinic acid derivatives via Suzuki cross-coupling