Mistrík Martin Ph.D.

Mistrík Martin Ph.D.'s picture
Phone: +420 585634873

Publications (Impact Factor Journals):

  • [31]
    ŠKROTT, Z., M. MISTRÍK, K. ANDERSEN, S. FRIIS, D. MAJERA, J. GURSKÝ, T. OŽDIAN, J. BARTKOVA, Z. TURI, P. MOUDRÝ, M. KRAUS, M. MEDVEDÍKOVÁ, J. VÁCLAVKOVÁ, P. DŽUBÁK, I. VROBEL, P. POUCKOVA, J. SEDLACEK, A. MIKLOVICOVA, A. KUTT, J. MATTOVA, C. DRIESSEN, Q. DOU, J. OLSEN, M. HAJDÚCH, B. CVEK, R. DESHAIES a J. BÁRTEK. Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4. Nature. 2017, 552(7684), 194-199. ISSN 0028-0836. IF: 40.137. PMID: 29211715
  • [30]
    TURI, Z., M. ŠENKYŘÍKOVÁ, M. MISTRÍK, J. BÁRTEK a P. MOUDRÝ. Perturbation of RNA Polymerase I transcription machinery by ablation of HEATR1 triggers the RPL5/RPL11-MDM2-p53 ribosome biogenesis stress checkpoint pathway in human cells. Cell Cycle. 2017, 17(1), 92-101. ISSN 1538-4101. IF: 3.530. PMID: 29143558
  • [29]
    PACULOVA, H., J. KRAMARA, S. SIMECKOVA, R. FEDR, K. SOUCEK, O. HYLSE, K. PARUCH, M. SVOBODA, M. MISTRÍK a J. KOHOUTEK. BRCA1 or CDK12 loss sensitizes cells to CHK1 inhibitors. Tumor Biology. 2017, 39(10), 1010428317727479. ISSN 1010-4283. IF: 3.650. PMID: 29025359
  • [28]
    VESELÁ, E., K. CHROMÁ, Z. TURI a M. MISTRÍK. Common Chemical Inductors of Replication Stress: Focus on Cell-Based Studies. Biomolecules. 2017, 7(1), pii: E19. ISSN 2218-273X . IF: 2.127. PMID: 28230817
  • [27]
    CHROMÁ, K., M. MISTRÍK, P. MOUDRÝ, J. GURSKÝ, M. LIPTAY, R. STRAUSS, Z. ŠKROTT, R. VRTEL, J. BARTKOVA, J. KRAMARA a J. BÁRTEK. Tumors overexpressing RNF168 show altered DNA repair and responses to genotoxic treatments, genomic instability and resistance to proteotoxic stress. Oncogene. 2017, 36(17), 2405-2422. ISSN 0950-9232 . IF: 7.932. PMID: 27841863
  • [26]
    BÉRESOVÁ, L., E. VESELÁ, I. CHAMRAD, J. VOLLER, M. YAMADA, T. FÜRST, R. LENOBEL, K. CHROMÁ, J. GURSKÝ, K. KŘÍŽOVÁ, M. MISTRÍK a J. BÁRTEK. Role of DNA Repair Factor Xeroderma Pigmentosum Protein Group C in Response to Replication Stress As Revealed by DNA Fragile Site Affinity Chromatography and Quantitative Proteomics. Journal of Proteome Research. 2016, 15(12), 4505-4517. ISSN 1535-3893 . IF: 4.268. PMID: 27794614
  • [25]
    KURFÜRSTOVÁ, D., J. BARTKOVA, R. VRTEL, A. MIČKOVÁ, A. BURDOVA, D. MAJERA, M. MISTRÍK, M. KRAL, F.R. SANTER, J. BOUCHAL a J. BÁRTEK. DNA damage signalling barrier, oxidative stress and treatment-relevant DNA repair factor alterations during progression of human prostate cancer. Molecular Oncology. 2016, 10(6), 879-894. ISSN 1574-7891. IF: 5.314. PMID: 26987799
  • [24]
    MISTRÍK, M., E. VESELÁ, T. FÜRST, H. HANZLIKOVA, I. FRYDRYCH, J. GURSKÝ, D. MAJERA a J. BÁRTEK. Cells and Stripes: A novel quantitative photo-manipulation technique. Scientific Reports. 2016, 6(-), Article Number: 19567. ISSN 2045-2322. IF: 4.259. PMID: 26777522
  • [23]
    KOMIS, G., M. MISTRÍK, O. SAMAJOVA, M. OVECKA, J. BÁRTEK a J. SAMAJ. Superresolution live imaging of plant cells using structured illumination microscopy. Nature Protocols. 2015, 10(8), 1248-1263. ISSN 1754-2189. IF: 9.646. PMID: 26203822
  • [22]
    MISTRÍK, M. a J. BÁRTEK. Editorial Material_ What a 'Ku'incidence!: parallel discoveries of a new DNA repair factor. Cell Death and Differentiation. 2015, 22(6), 888-889. ISSN 1350-9047. IF: IF (2014): 8.184. PMID: 25941165
  • [21]
    XU, G., J. CHAPMAN, I. BRANDSMA, J. YUAN, M. MISTRÍK, P. BOUWMAN, J. BARTKOVA, E. GOGOLA, D. WARMERDAM, M. BAZARAS, J. JASPERS, K. WATANABE, M. PIETERSE, K. KERSBERGEN, W. SOL, P. CELIE, P. SCHOUTEN, B. VAN DEN BROEK, A. SALMAN, M. NIEUWLAND, I. DE RINK, J. DE RONDE, K. JALINK, S. BOULTON, J. CHEN, D. VAN GENT, J. BÁRTEK, J. JONKERS, P. BORST a S. ROTTENBERG. REV7 counteracts DNA double-strand break resection and affects PARP inhibition. Nature. 2015, 521(7553), 541-544. ISSN 0028-0836. IF: 38.138. PMID: 25799992
  • [20]
    FUGGER, K., M. MISTRÍK, K. NEELSEN, Q. YAO , R. ZELLWEGER, A. KOUSHOLT, P. HAAHR, W. CHU, J. BÁRTEK, M. LOPES, I. HICKSON a C. SORENSEN. FBH1 Catalyzes Regression of Stalled Replication Forks. Cell Reports. 2015, 10(10), 1749-1757. ISSN 2211-1247. IF: 7.870. PMID: 25772361
  • [19]
    KANU, N., E. GRONROOS, P.. MARTINEZ, R.A. BURRELL, X.Y. GOH, J. BARTKOVA, A. MAYA-MENDOZA, M. MISTRÍK, A.J. ROWAN, H. PATEL, A. RABINOWITZ, P. EAST, G. WILSON, C.R. SANTOS, N. MCGRANAHAN, S. GULATI, M. GERLINGER, N.J. BIRKBAK, T. JOSHI, L.B. ALEXANDROV, M.R. STRATTON, T. POWLES, N. MATTHEWS, P.A. BATES, A. STEWART, Z. SZALLASI, J. LARKIN, J. BÁRTEK a C. SWANTON. SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair. Oncogene. 2015, 34(46), 5699-5708. ISSN 0950-9232. IF: 7.932. PMID: 25728682
  • [18]
    MAYA-MENDOZA, A., J. OSTRAKOVA, M. KOSAR, A. HALL., P. DUŠKOVÁ, M. MISTRÍK, J. MERCHUT-MAYA, Z. HODNY, J. BARTKOVA, C. CHRISTENSEN a J. BÁRTEK. Myc and Ras oncogenes engage different energy metabolism programs and evoke distinct patterns of oxidative and DNA replication stress. Molecular Oncology. 2015, 9(3), 601-616. ISSN 1574-7891. IF: 5.367. PMID: 25435281
  • [17]
    CHRISTENSEN, C., J. BARTKOVA, M. MISTRÍK, A. HALL., M.K. LANGE, U. RALFKIÆR, J. BÁRTEK a P. GULDBERG. A short acidic motif in ARF guards against mitochondrial dysfunction and melanoma susceptibility. Nature Communications. 2014, 5(5348), -. ISSN 2041-1723. IF: 11.470. PMID: 25370744
  • [16]
    OKA, Y., H. VARMARK, K. VITTING-SEERUP, P. BELI, J. WAAGE, A. HAKOBYAN, M. MISTRÍK, C. CHOUDHARY, M. ROHDE, S. BEKKER-JENSEN a N. MAILAND. UBL5 is essential for pre-mRNA splicing and sister chromatid cohesion in human cells. EMBO Reports. 2014, 15(9), 956-964. ISSN 1469-221X. IF: 9.055. PMID: 25092792
  • [15]
    KUMAR, A., M. MAZZANTI, M. MISTRÍK, M. KOSAR, G.V. BEZNOUSSENKO, A.A. MIRONOV, M. GARRE, D. PARAZZOLI, G. SHIVASHANKAR, G. SCITA, J. BÁRTEK a M. FOIANI. ATR Mediates a Checkpoint at the Nuclear Envelope in Response to Mechanical Stress. Cell. 2014, 158(3), 633-646. ISSN 0092-8674. IF: 32.242. PMID: 25083873
  • [14]
    JANSA, P., D. HOMOLKA, R. BLATNY, M. MISTRÍK, J. BÁRTEK a J. FOREJT. Dosage Compensation of an Aneuploid Genome in Mouse Spermatogenic Cells. Biology of Reproduction. 2014, 90(6), Article Number: 124. ISSN 0006-3363. IF: 3.318. PMID: 24790161
  • [13]
    KOMIS, G., M. MISTRÍK, O. SAMAJOVA, A. DOSKOCILOVA, M. OVECKA, P. ILLES, J. BÁRTEK a J. SAMAJ. Dynamics and Organization of Cortical Microtubules as Revealed by Superresolution Structured Illumination Microscopy. Plant Physiology. 2014, 165(1), 129-148. ISSN 0032-0889. IF: 6.841. PMID: 24686112
  • [12]
    BHATTACHARYYA, T., R. REIFOVA, S. GREGOROVA, P. SIMECEK, V. GERGELITS, M. MISTRÍK, I. MARTINCOVA, J. PIALEK a J. FOREJT. X Chromosome Control of Meiotic Chromosome Synapsis in Mouse Inter-Subspecific Hybrids. PLOS Genetics. 2014, 10(2), -. ISSN 1553-7404. IF: 7.528. PMID: 24516397
  • [11]
    YAMADA, M., K. WATANABE, M. MISTRÍK, E. VESELÁ, I. PROTIVÁNKOVÁ, N. MAILAND, M. LEE, H. MASAI, J. LUKÁŠ a J. BÁRTEK. ATR-Chk1-APC/CCdh1-dependent stabilization of Cdc7-ASK (Dbf4) kinase is required for DNA lesion bypass under replication stress. Genes & Development. 2013, 27(22), 2459-2472. ISSN 0890-9369. IF: 12.639. PMID: 24240236
  • [10]
    BÁRTEK, J., M. MISTRÍK a J. BARTKOVA. Androgen receptor signaling fuels DNA repair and radioresistance in prostate cancer. Cancer Discovery. 2013, 3(11), 1222-1224. ISSN 2159-8274. IF: 15.929. PMID: 24203954
  • [9]
    MISTRÍK, M. a J. KRAMARA. DNA damage-related ubiquitinations: one E1 that rules them all. Cell Cycle. 2012, 11(10), 1872-1877. ISSN 1538-4101. IF: 5.321. PMID: 22580454
  • [8]
    FALCK, J., J. FORMENT, J. COATES, M. MISTRÍK, J. LUKÁŠ, J. BÁRTEK a S.P. JACKSON. CDK targeting of NBS1 promotes DNA-end resection, replication restart and homologous recombination. EMBO Reports. 2012, 13(6), 561-568. ISSN 1469-221X. IF: 7.189. PMID: 22565321
  • [7]
    BÁRTEK, J., M. MISTRÍK a J. BARTKOVA. Thresholds of replication stress signaling in cancer development and treatment. Nature Structural & Molecular Biology. 2012, 19(1), 5-7. ISSN 1545-9993. IF: 11.902. PMID: 22218289
  • [6]
    JORDA, R., L. HAVLICEK, I.W. MCNAE, M.D. WALKINSHAW, J. VOLLER, A. STURC, J. NAVRATILOVA, M. KUZMA, M. MISTRÍK, J. BÁRTEK, M. STRNAD a V. KRYŠTOF. Pyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine: Evaluation of a Novel Selective Inhibitor of Cyclin-Dependent Kinases with Antiproliferative Activity. Journal of Medicinal Chemistry. 2011, 54(8), 2980-2993. ISSN 0022-2623. IF: 5.248. PMID: 21417417
  • [5]
    LÖFFLER, H., A. FECHTER, M. MATUSZEWSKA, R. SAFFRICH, M. MISTRÍK, J. MARHOLD, C. HORNUNG, F. WESTERMANN, J. BÁRTEK a A. KRÄMER. Cep63 Recruits Cdk1 to the Centrosome: Implications for Regulation of Mitotic Entry, Centrosome Amplification, and Genome Maintenance. Cancer Research. 2011, 71(6), 2129-2139. ISSN 0008-5472. IF: 7.856. PMID: 21406398
  • [4]
    BÁRTEK, J., M. MISTRÍK a J. BARTKOVA. Long-distance inflammatory and genotoxic impact of cancer in vivo. Proceedings of the National Academy of Sciences of the United States of America. 2010, 107(42), 17861-17862. ISSN 0027-8424. IF: 9.771. PMID: 20926747
  • [3]
    HODNY, Z., M. MISTRÍK a J. BÁRTEK. HERCulean giant orchestrates ubiquitin-mediated signaling on damaged chromosomes. Cell Cycle. 2010, 9(7), 1227-1228. ISSN 1538-4101. IF: 4.999. PMID: 20234179
  • [2]
    MISTRÍK, M. a J. BÁRTEK. Cyclin D3-dependent kinases in lymphoma: redundancy and implications for therapy. Cell Cycle. 2010, 9(3), 446-447. ISSN 1538-4101. IF: 4.999. PMID: 20130452
  • [1]
    BRULÍKOVÁ, L., S. KŘUPKOVÁ, M. LABORA, K. MOTYKA, L. HRADILOVÁ, M. MISTRÍK, J. BÁRTEK a J. HLAVÁČ. Synthesis and study of novel pH-independent fluorescent mitochondrial labels based on Rhodamine B. RSC Advances. 2016, 6(28), 23242-23251. ISSN 2046-2069 . IF: 3.108.

Patents, Utility models & other IP's :

[5] CULTURING KIT FOR MICROSCOPY OF ADHESIVELY GROWING CELL STRUCTURES, Priority Appl. CZ PUV 2015-31755
  1. Utility Model: CZ 29  265, Granted: 15. 3. 2016, Ownership: Palacky University Olomouc, Inventors: Mistrík MartinBártek Jiří

Status: Available 

[4] BIOLOGICAL INCUBATOR FOR STORAGE AND TRANSPORTATION OF BIOLOGICAL SAMPLES, ESPECIALLY CELL CULTURES, Priority Appl. CZ PUV 2015-30725
  1. Utility Model: CZ 28 195, Granted: 13. 5. 2015, Ownership: Technical University Brno, Palacky University Olomouc, Inventors: Paloušek David, Grepl Robert, Krejčí Petr, Vejlupek Josef, Mistrík Martin

Status: Available

[3] METHOD OF OBTAINING FOLLICULAR CELLS AND A DEVICE FOR CARRYING OUT THIS METHOD, Priority Appl. CZ PV 2012-871
  1. Patent: CZ 304 255, Granted: 18. 12. 2013, Ownership: Palacky University Olomouc, Inventors: Mistrík Martin, Bártek Jiří
  2. Patent: US 9,943,331, Granted: 17. 4. 2018, Ownership: Palacky University Olomouc, Inventors: Mistrík MartinBártek Jiří

Status: Available

[2] METHOD OF PRODUCTION OF SYNCHRONIZED ADHERENTLY GROWING CELL LINES AND DEVICE FOR CARRYING OUT SAID METHOD, Priority Appl. CZ PV 2009-236
  1. Patent: CZ 302 682, Granted: 20. 7. 2011, Ownership: Palacky University Olomouc, Inventors: Mistrík MartinBártek Jiří
  2. Patent: EP 2 419 503, Granted: 19. 12. 2012, Ownership: Palacky University Olomouc, Inventors: Mistrík Martin, Bártek Jiří

Status: Terminated

[1] DEVICE FOR PRODUCTION OF SYNCHRONIZED ADHERENTLY GROWING CELL LINES, Priority Appl. CZ PUV 2009-21114
  1. Utility Model: CZ 19 628, Granted: 11. 5. 2009, Ownership: Palacky University Olomouc, Inventors: Mistrík MartinBártek Jiří

Status: Terminated


Doctoral students mentor:

[2] Tereza Buchtová, Proteotoxic stress,
Ph.D. specialization: , status: Ongoing, from: 2018
[1] Zdeněk Škrott, The role of the ubiquitin-proteasome system in tumorigenesis and cancer treatment,
Ph.D. specialization: , status: Ongoing, from: 2014