Header image
Džubák Petr M.D., Ph.D.
E-mail:
petr.dzubak@upol.cz
Telefon:
+420 585632150, +420 604851158
Skupiny:
ÚMTM, LEM, PERSONÁL, VEDOUCÍ
O mně
Scientist and pediatrician involved in molecular and translational medicine (disease area oncology and infectious diseases), leader of research program Chemical Biology and Experimental Therapeutics at IMTM. Actively participated in the research of more than 20 national and international projects; member of advisory board of Cancer Research Foundation „Rakovina ve veřejná“, co-founder of spin-off company focused on manufacturing of molecular diagnostics. Published more than >140 papers and books/chapters, >3552 SCI citations, H-index 27, Prix de Pharmacie 2007 Ambassade de France – Sanofi-aventis, Premier Prix.
Specialties: Molecular and translational medicine, Oncology, Drug research and development, MOA, Drug resistance
Journals
Novel 5-Substituted Oxindole Derivatives as Bruton's Tyrosine Kinase Inhibitors: Design, Synthesis, Docking, Molecular Dynamics Simulation, and Biological Evaluation.
ACS Omega.
2024,
7(9),
8067-8081,
ISSN: 2470-1343,
PMID: 38405484,
Books & book chapters
Vývoj nových léčiv,
1. vyd,
Praha,
Galén,
2015,
11,
469-472,
ISBN: 978-80-7492-121-6,
Hmotnostní spektrometrie,
1. vyd,
Olomouc,
Univerzita Palackého v Olomouci,
2014,
2.2,
34-40,
ISBN: 978-80-244-3951-8,
Elektrochemické metody, (bio)senzory a čipové platformy,
1. vyd,
Olomouc,
Univerzita Palackého v Olomouci,
2014,
2.3,
43-44,
ISBN: 978-80-244-3951-8,
Intellectual property
METHOD OF IDENTIFICATION OF ENTITIES FROM MASS SPECTRA (Hruška)
- Published Application EP 18184710.4 under EP 3598135 (22.1.2020)
- Published Application PCT/EP2019/069552 under WO 2020/016428 (23.1.2020)
- Patent: JP 7218019. Granted: 27.1.2023. Ownership: Palacký University Olomouc. Inventors: HRUŠKA Miroslav, HAJDÚCH Marián, DŽUBÁK Petr
Status: Available
PYRIDINOPYRROLOPYRIMIDINE RIBONUCLEOSIDES FOR THERAPEUTIC USE (Veselovská)
- Patent: CZ 308104. Granted: 27. 11. 2019. Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University Olomouc. Inventors: VESELOVSKÁ Lucia, HOCEK Michal, HAJDÚCH Marián, DŽUBÁK Petr
- Published Application PCT/CZ2019/050008 under WO 2019/174657 (19.9.2019)
- Patent: EP 3765475. Granted: 15.9.2021. Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University Olomouc. Inventors: VESELOVSKÁ Lucia, HOCEK Michal, HAJDÚCH Marián, DŽUBÁK Petr
- Patent: US 11,299,510. Granted: 12.4.2022. Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University Olomouc. Inventors: VESELOVSKÁ Lucia, HOCEK Michal, HAJDÚCH Marián, DŽUBÁK Petr
- Patent: CA 3.090.343. Granted: 4.10.2022. Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University Olomouc. Inventors: VESELOVSKÁ Lucia, HOCEK Michal, HAJDÚCH Marián, DŽUBÁK Petr
- Patent: JP 6973761. Granted: 8.11.202. Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University Olomouc. Inventors: VESELOVSKÁ Lucia, HOCEK Michal, HAJDÚCH Marián, DŽUBÁK Petr
- Patent: AU 2019235042. Granted: 17.6.2021. Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University Olomouc. Inventors: VESELOVSKÁ Lucia, HOCEK Michal, HAJDÚCH Marián, DŽUBÁK Petr
Status: Available
DISULFIRAM I (Škrott)
- Patent: EP 3459526. Granted: 24.2.2021. Ownership: Palacký University Olomouc. Inventors: Škrott Zdeněk, Mistrík Martin, Hajdúch Marián, Bártek Jiří, Džubák Petr, Zbořil Radek.
- Published Application PCT/EP2018/076098 under WO 2019/063601 (4.4.2019)
- Patent: US 11,766,404. Granted: 26.9.2023. Ownership: Palacký University Olomouc. Inventors: Škrott Zdeněk, Mistrík Martin, Hajdúch Marián, Bártek Jiří, Džubák Petr, Zbořil Radek.
- Patent: AU 2018340510. Granted: 5.8.2021. Ownership: Palacký University Olomouc. Inventors: Škrott Zdeněk, Mistrík Martin, Hajdúch Marián, Bártek Jiří, Džubák Petr, Zbořil Radek.
- EP 18774061.9 - patent pending.
- Patent: IL 273652. Granted: 2.1.2024. Ownership: Palacký University Olomouc. Inventors: Škrott Zdeněk, Mistrík Martin, Hajdúch Marián, Bártek Jiří, Džubák Petr, Zbořil Radek.
- Patent: CA 3,076,855. Granted: 26.4.2022. Ownership: Palacký University Olomouc. Inventors: Škrott Zdeněk, Mistrík Martin, Hajdúch Marián, Bártek Jiří, Džubák Petr, Zbořil Radek.
- Patent: KR 10-2456683. Granted: 14.10.2022. Ownership: Palacký University Olomouc. Inventors: Škrott Zdeněk, Mistrík Martin, Hajdúch Marián, Bártek Jiří, Džubák Petr, Zbořil Radek.
- Patent: JP 7149624. Granted: 29.9.2022. Ownership: Palacký University Olomouc. Inventors: Škrott Zdeněk, Mistrík Martin, Hajdúch Marián, Bártek Jiří, Džubák Petr, Zbořil Radek.
- Patent: MX 396,552. Granted: 17.10.2022. Ownership: Palacký University Olomouc. Inventors: Škrott Zdeněk, Mistrík Martin, Hajdúch Marián, Bártek Jiří, Džubák Petr, Zbořil Radek.
Status: Available
Doctoral mentorship
Konečný Petr M.Sc.
Screening of chemical compounds´ biological activities in vitro
Stav:
Absolvoval od 2010 do 2016.
Rylová Gabriela M.Sc.
Identification of molecular targets of anticancer drugs by proteomic methods
Stav:
Absolvoval od 2009 do 2009.
Uniyal Vaishali
Kinase inhibitors in treatment of neurodegenerative disease
Stav:
Probíhající od 2018 do 2018.
Master mentorship
Václavková Jana M.Sc.
Proteomic profile of anticancer effect of clinically used plant alkaloids
Stav:
Absolvoval od 2011 do 2013.
Open positions
| Projekt: | Identification of molecular targets and mechanisms of drug resistance by cellular methods biology and proteomics |
|---|---|
| Vedoucí: | Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D. |
| K dispozici: | 2 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 2 places in full-time study |
| Projekt: | Utilization of the space of unprecedented covalent inhibitors |
|---|---|
| Vedoucí: | Dömling Alexander PhD., Džubák Petr M.D., Ph.D. |
| K dispozici: | 1 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 1 place in full-time study |
| Projekt: | Identification of molecular targets of antitumor drugs using methods of cell biology and proteomics |
|---|---|
| Vedoucí: | Džubák Petr M.D., Ph.D. |
| K dispozici: | 2 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 2 places in full-time study |
| Projekt: | Identification of proteomic biomarkers in tears of patients with neurodegenerative diseases |
|---|---|
| Vedoucí: | Džubák Petr M.D., Ph.D. |
| K dispozici: | 1 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 1 place in full-time study |
| Projekt: | Genetic and epigenetic biomarkers of cancer diseases |
|---|---|
| Vedoucí: | Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D. |
| K dispozici: | 3 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 3 places in full-time or combined form of study |
| Projekt: | Identification of proteomic biomarkers in exhaled air condensate in patients with systemic or pulmonary disease |
|---|---|
| Vedoucí: | Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D. |
| K dispozici: | 2 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 2 places in full-time study |
| Projekt: | Identification of proteomic biomarkers in tears of patients with brain cancer |
|---|---|
| Vedoucí: | Džubák Petr M.D., Ph.D. |
| K dispozici: | 1 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 1 place in full-time study |
| Projekt: | Antitumor drugs targeting nucleic acid metabolism |
|---|---|
| Vedoucí: | Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D. |
| K dispozici: | 2 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 2 places in full-time study |
| Projekt: | Targeted approaches to covalent inhibitors |
|---|---|
| Vedoucí: | Dömling Alexander PhD., Džubák Petr M.D., Ph.D. |
| K dispozici: | 1 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 1 place in full-time study |
| Projekt: | Synthesis of kinase inhibitors and their phenotypic chemoproteomic evaluation |
|---|---|
| Vedoucí: | Dömling Alexander PhD., Džubák Petr M.D., Ph.D. |
| K dispozici: | 1 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 1 place in full-time study |
| Projekt: | Identification of proteomic biomarkers in exhaled breath condensate patients with systemic or pulmonary disease |
|---|---|
| Vedoucí: | Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D. |
| K dispozici: | 2 |
| Určeno pro: | Doktorské studium |
| Projekt: | Anticancer drugs targeting nucleic acid metabolism |
|---|---|
| Vedoucí: | Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D. |
| K dispozici: | 2 |
| Určeno pro: | Doktorské studium |
| Projekt: | Genetic and epigenetic biomarkers in health and disease |
|---|---|
| Vedoucí: | Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D., Koudeláková Vladimíra Ph.D. |
| K dispozici: | 5 |
| Určeno pro: | Doktorské studium |
| Projekt: | Research and development of agents for cancer, neurodegenerative and infectious diseases |
|---|---|
| Vedoucí: | De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D. |
| K dispozici: | 5 |
| Určeno pro: | Doktorské studium |
| Projekt: | Identification of proteomic biomarkers in proximal fluids and tissues |
|---|---|
| Vedoucí: | Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D. |
| K dispozici: | 2 |
| Určeno pro: | Doktorské studium |
| Projekt: | Omic approaches in reproductive medicine |
|---|---|
| Vedoucí: | Džubák Petr M.D., Ph.D., Oždian Tomáš Ph.D. |
| K dispozici: | 1 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 1 place in full-time study |