Is there a relationship between the substrate preferences and structural flexibility of cytochromes P450?

OTYEPKA, M., K. BERKA, P. ANZENBACHER
Is there a relationship between the substrate preferences and structural flexibility of cytochromes P450?. Current Drug Metabolism. 2012, 13(2), 130-142, ISSN: 1389-2002, PMID: 22208528,