Doctoral

Open doctoral positions 2025/2026

 

Date and location of the entrance examination: 
June 4, 2025 – start at 10:00 AM
Institute of Molecular and Translational Medicine, Hněvotínská 5, Olomouc, Czech Republic, alternatively online. 

The level of general professional knowledge will be evaluated according to the result of the admission procedure and interview, the applicant's aptitude for scientific work, the applicant's previous experience with scientific and professional work (diploma thesis, professional lectures and publications, applicant’s scientific activities, motivation, etc.), language skills, preconditions for graduation. Students will be admitted to the study based on the above criteria, capacity of the supervisors and the training facility. The applicant selects from the listed topics and, in addition to the chosen doctoral study programme he/she also indicates the topic of the dissertation thesis in the application.

The doctoral study program "Molecular and Translational Medicine" is focused on understanding the molecular basis of human diseases, as well as possibilities for their diagnosis and treatment.

The program particularly emphasizes the identification of new molecular targets and disease biomarkers, the development of innovative therapeutic approaches, biomedical informatics, and personalized medicine. It aims to foster scientific and critical thinking in postgraduate students while deepening their theoretical and practical knowledge.

Application deadline is May 15, 2025.

Information about application submission is available here lf.upol.cz.

 

Project: Diagnosis and treatment of rare diseases
Supervisors: Hajdúch Marián M.D., Ph.D., Srovnal Josef M.D., Ph.D., Adam Tomáš Ph.D.
Available: 3
Intended for: Doctoral training
Summary: 3 full-time positions
Project: Bioinformatics processing of large datasets in clinical and preclinical studies
Supervisors: Hajdúch Marián M.D., Ph.D., Pavliš Petr Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 positions (full-time or part-time)
Project: Anticancer drugs targeting nucleic acid metabolism
Supervisors: Hajdúch Marián M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 full-time position
Project: Identification of molecular targets and mechanisms of resistance in anticancer drugs using cell biology and proteomics
Supervisors: Hajdúch Marián M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 full-time position
Project: New diagnostic, prognostic, and predictive factors in solid tumors
Supervisors: Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 positions (full-time or part-time)
Project: Identification of cellular stress pathways essential for cancer cell survival
Supervisors: Mistrík Martin Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 full-time position
Project: Innovative scaffold development using MCR chemistry for various drug targets
Supervisors: Patil Pravin Hasuram
Available: 1
Intended for: Doctoral training
Summary: 1 full-time position
Project: Analysis of cancer biomarkers using 2D plasmonic nanomaterials
Supervisors: Ranc Václav Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 full-time position
Project: Prediction of compound properties based on molecular representations
Supervisors: Polishchuk Pavlo Ph.D., M.Sc.
Available: 1
Intended for: Doctoral training
Summary: 1 full-time position
Project: Structural optimization of compounds to improve biological activity profiles
Supervisors: Polishchuk Pavlo Ph.D., M.Sc.
Available: 1
Intended for: Doctoral training
Summary: 1 full-time position
Project: Analysis of morphological compound profiles
Supervisors: Polishchuk Pavlo Ph.D., M.Sc.
Available: 1
Intended for: Doctoral training
Summary: 1 full-time position
Project: Mitochondrial and microglial dysfunction in tauopathies: effects of pathogenic TAU strains
Supervisors: Das Viswanath M.Sc., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 full-time position
Project: Identification of new derivatives targeting precancerous and tumor lesions and their mechanisms of action
Supervisors: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 full-time positions
Project: DNA replication in human pathophysiology
Supervisors: Moudrý Pavel Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 full-time position
Project: Natural compounds with anti tumor activity
Supervisors: Urban Milan Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 full-time positions
Project: New prognostic and predictive factors in solid tumors
Supervisors: Srovnal Josef M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 full-time positions
Project: Liquid biopsies in experimental and clinical oncology
Supervisors: Srovnal Josef M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 full-time positions
Project: Role of PD1 signaling in the immune response against solid tumors
Supervisors: De Sanctis Juan Bautista Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 1 position (full-time), 1 position (part-time)
Project: Early cognitive changes in aging and neurodegeneration
Supervisors: Stokin Gorazd Bernard
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Systems approaches to understanding aging and neurodegeneration
Supervisors: Stokin Gorazd Bernard
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: The role of axonal transport and pathology in neurodegeneration
Supervisors: Stokin Gorazd Bernard
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Search and study of the mechanism of action of new modulators of circadian rhythms for the therapy of civilization diseases
Supervisors: Voller Jiří Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Preclinical development of substances for molecular imaging
Supervisors: Petřík Miloš Assoc. Prof., PharmDr., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Omic approaches in reproductive medicine
Supervisors: Džubák Petr M.D., Ph.D., Oždian Tomáš Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Multimodal imaging methods for preclinical testing of new bioactive molecules
Supervisors: Nový Zbyněk Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Diagnosis and treatment of rare diseases
Supervisors: Hajdúch Marián M.D., Ph.D., Srovnal Josef M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Development of drugs in the field of small molecules 2 places in full-time study
Supervisors: Dömling Alexander PhD., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Physiology and pathophysiology of aging
Supervisors: Hajdúch Marián M.D., Ph.D., Voller Jiří Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Identification of molecular targets and mechanisms of resistance in antitumor drugs
Supervisors: Srovnal Josef M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Systems approaches to understanding aging and neurodegeneration
Supervisors: Das Viswanath M.Sc., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Role of axonal transport and pathology in neurodegeneration
Supervisors: Das Viswanath M.Sc., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Research and development of agents for cancer, neurodegenerative and infectious diseases
Supervisors: De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D.
Available: 5
Intended for: Doctoral training
Project: Isolation and analysis of membrane lipid rafts using a non-targeted metabolomics and lipidomics approach
Supervisors: Najdekr Lukáš Ph.D.
Available: 1
Intended for: Doctoral training
Project: Use of open-source software approaches for analysis of metabolomic and lipidomic clinical data
Supervisors: Najdekr Lukáš Ph.D.
Available: 1
Intended for: Doctoral training
Project: Identification of proteomic biomarkers in proximal fluids and tissues
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Preclinical development of molecular imaging agents
Supervisors: Petřík Miloš Assoc. Prof., PharmDr., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Plasmonic nanomaterials in cancer theranostics
Supervisors: Ranc Václav Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time or part-time study
Project: Ligand- and structure-based modeling of biologically active compounds
Supervisors: Polishchuk Pavlo Ph.D., M.Sc.
Available: 1
Intended for: Doctoral training
Project: Biologically active molecules and their therapeutic combinations
Supervisors: Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Cellular stress in health and disease
Supervisors: Mistrík Martin Ph.D., Moudrý Pavel Ph.D., Škrott Zdeněk Ph.D.
Available: 3
Intended for: Doctoral training
Project: Anticancer drugs targeting nucleic acid metabolism
Supervisors: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Identification of proteomic biomarkers in exhaled breath condensate patients with systemic or pulmonary disease
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Development of 3D pharmacophore signatures and their application in anticancer drug design
Supervisors: Polishchuk Pavlo Ph.D., M.Sc.
Available: 1
Intended for: Doctoral training
Project: Genetic and epigenetic biomarkers in health and disease
Supervisors: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D., Koudeláková Vladimíra Ph.D.
Available: 5
Intended for: Doctoral training
Project: Cellular fluxomic analysis for research of pathobiochemical processes
Supervisors: Adam Tomáš Ph.D.
Available: 1
Intended for: Doctoral training
Project: Research and development of small-molecule drugs
Supervisors: Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 full-time positions
Project: Identification of proteomic biomarkers in tears of patients with neurodegenerative diseases
Supervisors: Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Applied lipidomics approach in the search for new clinical biomarkers and elucidation of the structure of unknown lipid species
Supervisors: Najdekr Lukáš Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Application of untargeted lipidomics and metabolomics as a tool for generating hypotheses in personalized medicine
Supervisors: Najdekr Lukáš Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Epigenetic and genetic biomarkers of phenotypic traits
Supervisors: Drábek Jiří Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Identification of proteomic biomarkers in tears of patients with brain cancer
Supervisors: Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Liquid biopsies in experimental and clinical oncology
Supervisors: Srovnal Josef M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time or combined form of study
Project: New prognostic and predictive factors in solid tumors
Supervisors: Srovnal Josef M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time or combined form of study
Project: Identification of proteomic biomarkers in exhaled air condensate in patients with systemic or pulmonary disease
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Genetic and epigenetic biomarkers of cancer diseases
Supervisors: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D.
Available: 3
Intended for: Doctoral training
Summary: 3 places in full-time or combined form of study
Project: Multi-instance learning in chemoinformatics
Supervisors: Polishchuk Pavlo Ph.D., M.Sc.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Explainable artificial intelligence in chemoinformatics
Supervisors: Polishchuk Pavlo Ph.D., M.Sc.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: New chemoinformatic approaches to fragment-based drug discovery
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Modeling of biologically active compounds based on ligands and structure
Supervisors: Polishchuk Pavlo Ph.D., M.Sc.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Bioinformatics processing of big data within clinical and preclinical studies
Supervisors: Hajdúch Marián M.D., Ph.D., Pavliš Petr Ph.D.
Available: 3
Intended for: Doctoral training
Summary: 3 places in full-time or combined form of study
Project: Chemoinformatic approaches to drug design based on fragments
Supervisors: Polishchuk Pavlo Ph.D., M.Sc.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: New anti-inflammatory small molecules
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Innovative medicinal chemistry
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Innovative drugs for Parkinson's disease
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Discovery of new antitumor substances
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Discovery of new antibacterial substances
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Utilization of the space of unprecedented covalent inhibitors
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Innovative approaches to modifiers of protein interactions
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Identification of molecular targets of antitumor drugs using methods of cell biology and proteomics
Supervisors: Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Microsynthesis of drug candidates in medicinal chemistry
Supervisors: Dömling Alexander PhD.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Identification of molecular targets and mechanisms of drug resistance by cellular methods biology and proteomics
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: DNA damage signaling in the cellular response to stress
Supervisors: Mistrík Martin Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Search and characterization of substances for the therapy of congenital or acquired diseases caused by aberrant pre-mRNA splicing
Supervisors: Voller Jiří Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Synthesis of kinase inhibitors and their phenotypic chemoproteomic evaluation
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Targeted approaches to covalent inhibitors
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Decoding the binding principles of small molecules to RNA
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: New methods of targeted protein degradation
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Search and study of the mechanism of action of substances affecting the viability and motility of human spermatozoa
Supervisors: Voller Jiří Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Study of basic pharmacokinetic properties (ADME) of new drugs in preclinical development
Supervisors: Lišková Barbora Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Synthesis and characterization of 2D nanoplatforms as active drug carriers.
Supervisors: Ranc Václav Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time or combined form of study
Project: Modification of biologically active molecules leading to their improvement pharmacological properties
Supervisors: Dömling Alexander PhD.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Drug repurposing for the treatment and prevention of diseases
Supervisors: Hajdúch Marián M.D., Ph.D., Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Antitumor drugs targeting nucleic acid metabolism
Supervisors: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: The role of tumor hypoxia in the emergence of acquired resistance to drugs aimed at microtubules
Supervisors: Das Viswanath M.Sc., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Cellular fluxomic analysis for the research of pathobiochemical processes
Supervisors: Adam Tomáš Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time or combined form of study