Dömling Alexander PhD.

Journals

KHOSRAVIFARD, S., S. HOSSEINKHANI, N. BAKHTIARY, M. PEYVANDI, A. DÖMLING
Disruption of NLRP3 inflammasome assembly via ligand-induced remodeling of pyrin domain interfaces. Scientific Reports. 2026, ISSN: 2045-2322, PMID: 41513945,  PDF.
PATIL, P., R. FUSCO, I. CAPRIELLO, Z. GUAN, A. BHALKIKAR, J. GIBBONS, T. KORBA, S. BASKHYRTSEV, O. TKACHENKO, A. DÖMLING
Precipitation-first synthesis and deep profiling of a 1200-member acrylamide library for covalent drug discovery. Green Chemistry . 2025, 27(45), 14640-14647, ISSN: 1463-9262, PMID: 41181219,  PDF.
JURÁŠEK, M., E. DRABEROVA, J. ŘEHULKA, S. GURSKÁ, A. IVANOVA (NIKONENKO), P. POLISHCHUK, K. BURGETOVÁ JEČMEŇOVÁ, J. FAHNRICH, A. MARESOVA, J. TAUCHEN, A. REYES ROMERO, A. DÖMLING, M. HAJDÚCH, P. DRAŠAR, P. DRABER, P. DŽUBÁK
Colchicine-BODIPY Probes: Evidence for the Involvement of Intracellular Membranes in the Targeting of Colchicine to Tubulin. ACS pharmacology & translational science. 2025, 8(7), 1965-1985, ISSN: 2575-9108, PMID: 40672674,  PDF.

Postdoctoral mentorship

Reyes Romero Atilio Ph.D.

Accellerated Drug Discovery and Screening

Status: Ongoing.

Doctoral mentorship

Masineni Samantha

Synthesis and characterization of 2D nanoplatforms as active drug carriers

Status: Ongoing from 2024.
Mukim Mayur Shashikan

Synthesis and characterization of 2D nanoplatforms as active drug carriers

Status: Ongoing from 2024.
Salama Kaoud MSc.

Synthesis and characterization of 2D nanoplatforms as active drug carriers

Status: Ongoing from 2024.

Open positions

Project: New anti-inflammatory small molecules
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Microsynthesis of drug candidates in medicinal chemistry
Supervisors: Dömling Alexander PhD.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Innovative approaches to modifiers of protein interactions
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Utilization of the space of unprecedented covalent inhibitors
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Discovery of new antibacterial substances
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Discovery of new antitumor substances
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Innovative drugs for Parkinson's disease
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Innovative medicinal chemistry
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Decoding the binding principles of small molecules to RNA
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Targeted approaches to covalent inhibitors
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Synthesis of kinase inhibitors and their phenotypic chemoproteomic evaluation
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Modification of biologically active molecules leading to their improvement pharmacological properties
Supervisors: Dömling Alexander PhD.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: New methods of targeted protein degradation
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Drug repurposing for the treatment and prevention of diseases
Supervisors: Hajdúch Marián M.D., Ph.D., Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: New chemoinformatic approaches to fragment-based drug discovery
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Development of drugs in the field of small molecules 2 places in full-time study
Supervisors: Dömling Alexander PhD., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study