Dömling Alexander PhD.

Journals

VAN DER STRAAT, R., R. OERLEMANS, Y. CONG, J. BOXMA, R. BULAI, C. RIO-BERGE, L. KOEKEMOER, T. ZARGANES-TZITZIKAS, M. GUAN, P. MARPLES, F. REGGIORI, M. GROVES, A. DÖMLING
Ugi-Tetrazole-Derived α‑Aminomethyl Scaffolds Reveal Unexpected Binding Modes in SARS-CoV‑2 3CLpro. ACS Medicinal Chemistry Letters. 2026, 17(4), 856-865, ISSN: 1948-5875, PMID: 41982734,  PDF.
VAN DER STRAAT, R., J. KALINOWSKA-TLUSCIK, K. KURPIEWSKA, A. DÖMLING
Systematic Expansion of an Ugi-Based Multicomponent Synthesis of Tetrasubstituted Imidazoles. ACS Omega. 2026, 11(13), 20889-20894, ISSN: 2470-1343, PMID: 41970876,  PDF.
CHEN, S., M. CAL, Q. MONDILE, R. OERLEMANS, M. MUKIM, A. DÖMLING, O. BISHOP, P. MASER, M. GROVES
Repurposing of Inhibitors of Plasmodial Aspartate Transcarbamoylase Toward Trypanosoma Cruzi. ChemMedChem. 2026, 21(6), e202500817, ISSN: 1860-7179, PMID: 41886248,  PDF.

Postdoctoral mentorship

Reyes Romero Atilio Ph.D.

Accellerated Drug Discovery and Screening

Status: Ongoing.

Doctoral mentorship

Masineni Samantha

Synthesis and characterization of 2D nanoplatforms as active drug carriers

Status: Ongoing from 2024.
Mukim Mayur Shashikan

Synthesis and characterization of 2D nanoplatforms as active drug carriers

Status: Ongoing from 2024.
Salama Kaoud MSc.

Synthesis and characterization of 2D nanoplatforms as active drug carriers

Status: Ongoing from 2024.

Open positions

Project: New anti-inflammatory small molecules
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Microsynthesis of drug candidates in medicinal chemistry
Supervisors: Dömling Alexander PhD.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Innovative approaches to modifiers of protein interactions
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Utilization of the space of unprecedented covalent inhibitors
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Discovery of new antibacterial substances
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Discovery of new antitumor substances
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Innovative drugs for Parkinson's disease
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Innovative medicinal chemistry
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Decoding the binding principles of small molecules to RNA
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Targeted approaches to covalent inhibitors
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Synthesis of kinase inhibitors and their phenotypic chemoproteomic evaluation
Supervisors: Dömling Alexander PhD., Džubák Petr M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Modification of biologically active molecules leading to their improvement pharmacological properties
Supervisors: Dömling Alexander PhD.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: New methods of targeted protein degradation
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Drug repurposing for the treatment and prevention of diseases
Supervisors: Hajdúch Marián M.D., Ph.D., Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: New chemoinformatic approaches to fragment-based drug discovery
Supervisors: Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Development of drugs in the field of small molecules 2 places in full-time study
Supervisors: Dömling Alexander PhD., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study