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Hajdúch Marián M.D., Ph.D.

Journals

NGO, O., R. CHLOUPKOVA, D. CIBULA, J. SLAMA, L. MANDELOVA, K. HEJDUK, M. HAJDÚCH, P. MINKA, V. KOUDELÁKOVÁ, H. JAWOREK, M. TRNKOVA, P. VANEK, V. DVORAK, L. DUŠEK, O. MAJEK
Direct mailing of HPV self-sampling kits to women aged 50-65 non-participating in cervical screening in the Czech Republic. European Journal of Public Health. 2024, ISSN: 1101-1262, PMID: 38224266,
GUTIERREZ, J., H. RAMIREZ, E. FERNANDEZ-MOREIRA, M. ACOSTA, M. MIJARES, J. DE SANCTIS, S. GURSKÁ, P. DŽUBÁK, M. HAJDÚCH, L. LABRADOR-FAGÚNDEZ, B. STELLA, L. DIAZ-PEREZ, G. BENAIM, J. CHARRIS
Synthesis, Antimalarial, Antileishmanial, and Cytotoxicity Activities and Preliminary In Silico ADMET Studies of 2-(7-Chloroquinolin-4-ylamino)ethyl Benzoate Derivatives. Pharmaceuticals . 2023, 16(12), 1709, ISSN: 1424-8247, PMID: 38139835,
Isoform-Directed Control of c-Myc Functions: Understanding the Balance from Proliferation to Growth Arrest. International Journal of Molecular Sciences. 2023, 24(24), 17524, ISSN: 1422-0067, PMID: 38139353,

Books & book chapters

Laboratory Techniques in Cellular and Molecular Medicine, 1.vyd., Olomouc, Palacky University, 2021, 436 s, Dedication: LO1304, ISBN: 978-80-244-6049-9,
Predictive Cancer Biomarkers: Current Practice and Future Challenges, 1.vyd, Boca Raton, CRC Press, 2019, 7.5, 383-394, ISBN: 978-1-4987-6258-8,
BOUCHALOVÁ, K., M. HAJDÚCH, J. BOUCHAL, A. HLOBILKOVA, M. HOUDOVÁ MEGOVÁ, M. HUDCOVÁ, V. KOUDELÁKOVÁ, J. MEDALOVA, J. SROVNAL, R. TROJANEC
Prediktivní a prognostická onkologie, 1. vyd, Olomouc, Univerzita Palackého v Olomouci, 2016, 122 s, Dedication: CZ.1.07/2.3.00/09.0089, ISBN: 978-80-244-3188-8,

Intellectual property

MCOPPB FOR USE AS MEDICAMENT (Mistrík)
  1. Published Application EP 18166780.9 under EP 3552605 (16.10.2019)
  2. Published Application PCT/CZ2019/059320 under WO 2019/197564 (17.10.2019)

Status: Patent pending, Available

CARBONIC ANHYDRASE INHIBITORS AND METHOD OF THEIR PRODUCTION (Řezáčová)
  1. Published Application PV 2011-676 (2.5.2013)
  2. Published Application PCT/CZ2012/000106 under WO 2013/060307 (2.5.2013)
  3. Patent: EP 2771015; Granted: 16.3.2016; Ownership: Institute of Organic Chemistry and Biochemistry CAS, Institute of Molecular Genetics CAS, Institute of Inorganic Chemistry CAS, Palacky University Olomouc; Inventors: Brynda Jiří, Cígler Petr, Gruner Bohumír, Maloy Řezáčová Pavlína, Mader Pavel, Šícha Václav, Bakardijev Mario, Džubák PetrHajdúch Marián
  4. Patent: US 9,290,529; Granted: 22.3.2016; Ownership: Institute of Organic Chemistry and Biochemistry CAS, Institute of Molecular Genetics CAS, Institute of Inorganic Chemistry CAS, Palacky University Olomouc; Inventors: Brynda Jiří, Cígler Petr, Gruner Bohumír, Maloy Řezáčová Pavlína, Mader Pavel, Šícha Václav, Bakardijev Mario, Džubák PetrHajdúch Marián

Status: Terminated

BIOAVAILABLE DITHIOCARBAMATE-METAL COMPLEX NANOPARTICLES, METHOD OF PREPARATION AND USE THEREOF "DISULFIRAM I" (Škrott)
  1. Patent: EP 3459526. Granted: 24.2.2021. Ownership: Palacky University, Olomouc. Inventors: Škrott Zdeněk, Mistrík Martin, Hajdúch Marián, Bártek Jiří, Džubák PetrZbořil Radek.
  2. Published Application PCT/EP2018/076098 under WO 2019/063601 (4.4.2019)
  3. Patent: AU 2018340510. Granted: 5.8.2021. Ownership: Palacký University Olomouc. Inventors: Škrott ZdeněkMistrík MartinHajdúch MariánBártek JiříDžubák PetrZbořil Radek.
  4. Patent: CA 3,076,855. Granted: 26.4.2022. Ownership: Palacký University Olomouc. Inventors: Škrott ZdeněkMistrík MartinHajdúch Marián, Bártek Jiří, Džubák PetrZbořil Radek.
  5. Patent: KR 10-2456683. Granted: 14.10.2022. Ownership: Palacký University Olomouc. Inventors: Škrott ZdeněkMistrík MartinHajdúch Marián, Bártek Jiří, Džubák PetrZbořil Radek.
  6. Patent: JP 2020-537873. Granted: 29.9.2022. Ownership: Palacký University Olomouc. Inventors: Škrott ZdeněkMistrík MartinHajdúch Marián, Bártek Jiří, Džubák PetrZbořil Radek.
  7. Patent: MX 396,552. Granted: 17.10.2022. Ownership: Palacký University Olomouc. Inventors: Škrott ZdeněkMistrík MartinHajdúch Marián, Bártek Jiří, Džubák PetrZbořil Radek.

Status: Available

Postdoctoral mentorship

Dvořanová Štěpánková Jana Ph.D.

Novel Carborane Based Inhibitors of Carbonic Anhydrase IX

Status: Ongoing.
Varanasi Lakshman Ph.D.

Identification and validation of serum-based biomarkers of gastrointestinal cancer in a mouse xenograft model

Status: Ongoing.
Agrawal Khushboo Ph.D.

Status: Ongoing.

Doctoral mentorship

Ondra Martin M.Sc.

Development and validation of luminescent HTS tool for discovery and optimization of novel combination of CFTR correctors and modifiers

Status: Ongoing from 2017.
Ziaei Nikta

Preparation of 3D cultures for high-throughput screening

Status: Ongoing from 2023.
Kubíčková Agáta

Cellular models for optical screening of biologically active compounds

Status: Ongoing from 2016.

Open positions

Project: Identification of molecular targets and mechanisms of drug resistance by cellular methods biology and proteomics
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Genetic and epigenetic biomarkers of cancer diseases
Supervisors: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D.
Available: 3
Intended for: Doctoral training
Summary: 3 places in full-time or combined form of study
Project: Identification of proteomic biomarkers in exhaled air condensate in patients with systemic or pulmonary disease
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Study of basic pharmacokinetic properties (ADME) of new drugs in preclinical development
Supervisors: Lišková Barbora Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Antitumor drugs targeting nucleic acid metabolism
Supervisors: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Drug repurposing for the treatment and prevention of diseases
Supervisors: Hajdúch Marián M.D., Ph.D., Dömling Alexander PhD.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Bioinformatics processing of big data within clinical and preclinical studies
Supervisors: Hajdúch Marián M.D., Ph.D., Pavliš Petr Ph.D.
Available: 3
Intended for: Doctoral training
Summary: 3 places in full-time or combined form of study
Project: Identification of molecular targets and mechanisms of resistance in antitumor drugs
Supervisors: Srovnal Josef M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Identification of proteomic biomarkers in exhaled breath condensate patients with systemic or pulmonary disease
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Diagnosis and treatment of rare diseases
Supervisors: Hajdúch Marián M.D., Ph.D., Srovnal Josef M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Genetic and epigenetic biomarkers in health and disease
Supervisors: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D., Koudeláková Vladimíra Ph.D.
Available: 5
Intended for: Doctoral training
Project: Physiology and pathophysiology of aging
Supervisors: Hajdúch Marián M.D., Ph.D., Voller Jiří Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Anticancer drugs targeting nucleic acid metabolism
Supervisors: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Development of drugs in the field of small molecules 2 places in full-time study
Supervisors: Dömling Alexander PhD., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Identification of proteomic biomarkers in proximal fluids and tissues
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Biologically active molecules and their therapeutic combinations
Supervisors: Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: Research and development of agents for cancer, neurodegenerative and infectious diseases
Supervisors: De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D.
Available: 5
Intended for: Doctoral training