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Phone: +420 585634855
Groups: IMTM, LEM, STAFF

About me

Positions:
researcher (drug screening, bio-/cheminformatician)
Institute of Molecular and Translational Medicine, Faculty of Medicine & Dentistry, Palacky University
since 2011

researcher (biology of stress and aging)
Department of Experimental Biology, Faculty of Science, Palacký University
since 2022

researcher (biology of stress and aging)
Laboratory of Growth Regulators, Institute of Experimental Botany AS CR & Palacký University
2010-2022

Education:
Palacký University, Faculty of Science, Olomouc, Czech Republic
PhD - biology

Charles University - Pharmaceutical Faculty, Hradec Králové - Czech Republic
MSc - pharmacy
 

Masaryk University, Faculty of Science, Brno, Czech Republic
MSc - molecular biology/genetics



Research Interests:
- biology of stress and aging (human cells, C. elegans, water bears)
- circadian rhythms
- drug screening ( circadian rhythm modulators, cytoprotection,  mitochondrial diseases,  parasitic worms,  ...)
- bio- and cheminformatics (identification of mechanism of drug action, comparison of drugs based on biological activity profiles, image analysis, machine learning)

Teaching:
Biogerontology
Drug Discovery
Biology of Circadian Rhythms and Sleep
Biology of Reproduction
 

Journals

KADLECOVA, A., K. DZEDULIONYTE MÜLDÜR, M. PERINA, K. BIELESZOVA, C. ZHANG, D. KOVÁŘÍČEK, E. VALDERAS-GARCIA, D. VÍTEK, M. VALIKONYTE, A. SACKUS, J. SOLOVJOVA, V. MALINAUSKIENE, K. DOLEZAL, O. NOVAK, F. GRUNDLER, P. ROY, M. MARTINEZ-VALLADARES, J. VOLLER, A. SCHLEKER
Synthesis, Anthelmintic Activity, and Mechanism of Action of 5-Aryl-1 H-indoles. Journal of Agricultural and Food Chemistry. 2025, ISSN: 0021-8561 , PMID: 41401077,
MAKOVA, B., V. MIK, B. LIŠKOVÁ, L. DRASAROVA, M. MEDVEDÍKOVÁ, A. HORINKOVA, P. VOJTA, M. ZATLOUKAL, L. PLÍHALOVÁ, M. HONIG, K. DOLEZAL, K. FOREJT, T. OŽDIAN, M. HAJDÚCH, M. STRNAD, J. VOLLER
Correction of aberrant splicing of ELP1 pre-mRNA by kinetin derivatives - A structure activity relationship study. European Journal of Medicinal Chemistry. 2024, ISSN: 0223-5234, PMID: 39756144,  PDF.
SUSHOVAN, J., G. GONZALES, D. VÍTEK, M. KVASNICOVA, S. STEPANKOVA, M. STRNAD, J. VOLLER, K. CHANDA
Novel neuroprotective 5,6-dihydropyrido[2',1':2,3]imidazo[4,5-c]quinoline derivatives acting through cholinesterase inhibition and CB2 signaling modulation. European Journal of Medicinal Chemistry. 2024, 276, 116592, ISSN: 0223-5234, PMID: 39013357,  PDF.

Intellectual property

HETEROCYCLIC COMPOUNDS FOR THE PREVENTION AND THERAPY OF CIRCADIAN RHYTHM DISORDERS - PV 2022-227 (Voller)
  1. Published Application: PCT/CZ2023/050029 under WO 2023/232171 (7.12.2023)
  2. Published Application US 18/868,011 under US 2025346601 (13.11.2025)
  3. Patent: EP 4532498. Granted: 29.10.2025. Ownership: Palacký University Olomouc; Institute of Physiology CAS. Inventors: VOLLER Jiří, MIK Václav, DOKONALOVÁ Markéta, SLÁDEK Martin, SUMOVÁ Alena, HAJDÚCH Marián, STRNAD Miroslav. 

Status: Available

N-(FURAN-2-YLMETHYL)-7H-PURIN-6-AMINE FOR TREATMENT OF CIRCADIAN RHYTHM DISEASES, DISORDERS AND DYSFUNCTIONS - PV 2019-757 (Voller) KINETIN
  1. Patent: CZ 310035. Granted: 18.4.2024. Ownership: Palacký University Olomouc; Institute of Physiology CAS. Inventors: VOLLER Jiří, SLÁDEK Martin, HAJDÚCH Marián, SUMOVÁ Alena, STRNAD Miroslav
  2. Published Application PCT/CZ2020/050094 under WO 2021/115502 (17.6.2021)
  3. Patent: US 12,558,358. Granted: 24.2.2026. Ownership: Palacký University Olomouc; Institute of Physiology CAS. Inventors: VOLLER Jiří, SLÁDEK Martin, HAJDÚCH Marián, SUMOVÁ Alena, STRNAD Miroslav
  4. Patent: EP 4072555. Granted: 22.1.2025. Ownership: Palacký University Olomouc; Institute of Physiology CAS. Inventors: VOLLER Jiří, SLÁDEK Martin, HAJDÚCH Marián, SUMOVÁ Alena, STRNAD Miroslav

Status: Available

Doctoral mentorship

Vítek Dominik

Study of neurodegeneration and aging on model organisms

Status: Ongoing from 2019.

Master mentorship

Voller Jiří Ph.D.

High-throughput screenining for anti-aging and neuroprotective compounds

Status: Ongoing from 2022.

Drozdová Barbora

Searching for neuroprotective substances using high-format screening

Status: Graduated from 2024 to 2025.

Szymczyskova Beata

Isolation of tardigrades from the environment and their characterization

Status: Graduated from 2024 to 2025.

Bachelor mentorship

Pertlová Markéta

Identification of genes related to cell death and cell cycle blockage in the genome of tardigrades.

Status: Graduated from 2024 to 2025.

Open positions

1 Molecular and cellular biology
Project: Search and characterization of substances for the therapy of congenital or acquired diseases caused by aberrant pre-mRNA splicing
Supervisors: Voller Jiří Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
1 Chemical biology and experimental therapeutics
Project: Search and study of the mechanism of action of substances affecting the viability and motility of human spermatozoa
Supervisors: Voller Jiří Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
2 Molecular and Translational Medicine
Project: Physiology and pathophysiology of aging
Supervisors: Hajdúch Marián M.D., Ph.D., Voller Jiří Ph.D.
Available: 2
Intended for: Doctoral training
Summary: 2 places in full-time study
Project: Search and study of the mechanism of action of new modulators of circadian rhythms for the therapy of civilization diseases
Supervisors: Voller Jiří Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study