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Najdekr Lukáš Ph.D.

Journals

ALIMAJSTOROVIC, Z., S. MOLLAN, O. GRECH, J. MITCHELL, A. YIANGOU, M. THALLER, H. LYONS, M. SASSANI, S. SENEVIRATNE, T. HANCOX, A. JANKEVICS, L. NAJDEKR, W. DUNN, A. SINCLAIR
Dysregulation of Amino Acid, Lipid, and Acylpyruvate Metabolism in Idiopathic Intracranial Hypertension: A Non-targeted Case Control and Longitudinal Metabolomic Study. Journal of Proteome Research. 2022, 22(4), 1127-1137, ISSN: 1535-3893, PMID: 36534069,
PURIS, E., Š. KOUŘIL, L. NAJDEKR, S. AURIOLA, S. LOPPI, P. KORHONEN, M. GOMEZ-BUDIA, G. FRICKER, K. KANNINEN, T. MALM, D. FRIEDECKÝ, M. GYNTHER
Metabolomic, lipidomic and proteomic characterisation of lipopolysaccharide-induced inflammation mouse model. Neuroscience. 2022, 496, 165-178, ISSN: 0306-4522, PMID: 35636730,  PDF.
KVASNIČKA, A., D. FRIEDECKÝ, A. TICHA, R. HYSPLER, H. JANEČKOVÁ, R. BRUMAROVÁ, L. NAJDEKR, Z. ZADAK
SLIDE-Novel Approach to Apocrine Sweat Sampling for Lipid Profiling in Healthy Individuals. International Journal of Molecular Sciences. 2022, 22(15), 8054, ISSN: 1422-0067, PMID: 34360820,  PDF.

Master mentorship

Pokorná Natálie

Development and validation of LC/MS assay for analyses of fat-soluble vitamins

Status: Graduated from 2021 to 2023.

Bachelor mentorship

Machálková Markéta

Untargeted metabolomics of T-lymphoblastic leukemia cells affected by quinolinone derivative

Status: Graduated from 2011 to 2013.
Šťastná Veronika

Metabolomic analysis of mouse plasma using aminopropyl column and TripleQ-MS

Status: Graduated from 2011 to 2013.
Mádrová Lucie M.Sc

Analysis of lipids in blood stains for the diagnosis of inherited metabolic disorders

Status: Graduated from 2011 to 2013.

Open positions

Project: Application of untargeted lipidomics and metabolomics as a tool for generating hypotheses in personalized medicine
Supervisors: Najdekr Lukáš Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Applied lipidomics approach in the search for new clinical biomarkers and elucidation of the structure of unknown lipid species
Supervisors: Najdekr Lukáš Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Use of open-source software approaches for analysis of metabolomic and lipidomic clinical data
Supervisors: Najdekr Lukáš Ph.D.
Available: 1
Intended for: Doctoral training
Project: Isolation and analysis of membrane lipid rafts using a non-targeted metabolomics and lipidomics approach
Supervisors: Najdekr Lukáš Ph.D.
Available: 1
Intended for: Doctoral training
Project: Vitamin analysis in human plasma cohort by application of UHPLC-MS
Supervisors: Najdekr Lukáš Ph.D.
Available: 1
Intended for: Bachelor training
Summary: Description: The main goal would be to learn basic analytical skills in the metabolomics laboratory. Starting with sample preparation (different types of extractions), followed by data acquisition on the LCMS analytical platform. The last step is a biological interpretation of measured data; in this case, the effects of vitamin deficiency or overdose on the human organism.