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Hajdúch Marián M.D., Ph.D.

Journals

VELAVAPALLI, V., V. MADDIPATI, S. GURSKÁ, N. ANNADURAI, B. LIŠKOVÁ, N. KATARI, P. DŽUBÁK, M. HAJDÚCH, V. DAS, R. GUNDLA
Novel 5-Substituted Oxindole Derivatives as Bruton's Tyrosine Kinase Inhibitors: Design, Synthesis, Docking, Molecular Dynamics Simulation, and Biological Evaluation. ACS Omega. 2024, 7(9), 8067-8081, ISSN: 2470-1343, PMID: 38405484,  PDF.
NGO, O., R. CHLOUPKOVA, D. CIBULA, J. SLAMA, L. MANDELOVA, K. HEJDUK, M. HAJDÚCH, P. MINKA, V. KOUDELÁKOVÁ, H. JAWOREK, M. TRNKOVA, P. VANEK, V. DVORAK, L. DUŠEK, O. MAJEK
Direct mailing of HPV self-sampling kits to women aged 50-65 non-participating in cervical screening in the Czech Republic. European Journal of Public Health. 2024, 34(2), 361-367, ISSN: 1101-1262, PMID: 38224266,
GUTIERREZ, J., H. RAMIREZ, E. FERNANDEZ-MOREIRA, M. ACOSTA, M. MIJARES, J. DE SANCTIS, S. GURSKÁ, P. DŽUBÁK, M. HAJDÚCH, L. LABRADOR-FAGÚNDEZ, B. STELLA, L. DIAZ-PEREZ, G. BENAIM, J. CHARRIS
Synthesis, Antimalarial, Antileishmanial, and Cytotoxicity Activities and Preliminary In Silico ADMET Studies of 2-(7-Chloroquinolin-4-ylamino)ethyl Benzoate Derivatives. Pharmaceuticals . 2023, 16(12), 1709, ISSN: 1424-8247, PMID: 38139835,  PDF.

Intellectual property

SUBSTITUTED HETEROPENTADIENO-PYRROLOPYRIMIDINE RIBONUCLEOSIDES FOR THERAPEUTIC USE (Hocek)
  1. Patent: CZ 307334. Granted: 2.5.2018. Ownership: Institute of Organic Chemistry and Biochemistry CAS; Palacký University Olomouc. Inventors: HOCEK Michal, TOKARENKO Anna, SMOLEŃ Sabina, DŽUBÁK PetrHAJDÚCH Marián
  2. Published application PCT/CZ2017/050031 under WO 2018/024265 (8.2.2018)
  3. Patent: EP 3494122. Granted: 18.9.2019. Ownership: Institute of Organic Chemistry and Biochemistry CAS; Palacký University Olomouc. Inventors: HOCEK Michal, TOKARENKO Anna, SMOLEŃ Sabina, DŽUBÁK PetrHAJDÚCH Marián
  4. Patent: US 10,730,905. Granted: 4.8.2020. Ownership: Institute of Organic Chemistry and Biochemistry CAS; Palacký University Olomouc. Inventors: HOCEK Michal, TOKARENKO Anna, SMOLEŃ Sabina, DŽUBÁK PetrHAJDÚCH Marián
  5. Patent: JP 6685475. Granted: 2.4.2020. Ownership: Institute of Organic Chemistry and Biochemistry CAS; Palacký University Olomouc. Inventors: HOCEK Michal, TOKARENKO Anna, SMOLEŃ Sabina, DŽUBÁK PetrHAJDÚCH Marián
  6. Patent: CA 3.031.049. Granted: 7.7.2020. Ownership: Institute of Organic Chemistry and Biochemistry CAS; Palacký University Olomouc. Inventors: HOCEK Michal, TOKARENKO Anna, SMOLEŃ Sabina, DŽUBÁK PetrHAJDÚCH Marián

Status: Available

FLUORESCENT DERIVATIVE FOR NON-CATALYTIC LABELING OF NUCLEIC ACID AND PEPTIDE COMPONENTS (Jedináková)
  1. Utility Model: CZ 30136, Granted: 13.12.2016, Ownership: Palacký University Olomouc, Inventors: Jedináková Petra, Hlaváč JanVáclavková Jana, Konečný Petr, Džubák Petr, Hajdúch Marián

Status: Terminated

SUBSTITUTED THIENOPYRROLOPYRIMIDINE RIBONUCLEOSIDES FOR THERAPEUTIC USE (Hocek)
  1. Published Application PCT/CZ2016/050021 under WO 2018/001393 (4.1.2018)
  2. Patent: EP 3478701. Granted: 10.8.2022. Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University Olomouc. Inventors: HOCEK Michal, TICHÝ Michal, HAJDÚCH MariánDŽUBÁK Petr
  3. Patent: US 10,414,788. Granted: 17.9.2019. Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University Olomouc. Inventors: HOCEK Michal, TICHÝ Michal, HAJDÚCH MariánDŽUBÁK Petr
  4. Patent: JP 6650074. Granted: 21.1.2020.  Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University Olomouc. Inventors: HOCEK Michal, TICHÝ Michal, HAJDÚCH MariánDŽUBÁK Petr
  5. Patent: CA 3.029.170. Granted: 16.2.2021. Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacký University, Olomouc. Inventors: HOCEK Michal, TICHÝ Michal, HAJDÚCH MariánDŽUBÁK Petr

Status: Terminated

Doctoral mentorship

Lenart Lukáš M.Sc.

Molecular basis of rare diseases and molecular targets

Stav: Probíhající od 2023.
Mečiarová Tatiana

Mechanisms of action and resistance of anticancer drugs

Stav: Probíhající od 2024.
Šamaj Matej

Anticancer drugs targeting nucleic acid metabolism

Stav: Probíhající od 2024.

Open positions

Projekt: Identification of molecular targets and mechanisms of drug resistance by cellular methods biology and proteomics
Vedoucí: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Souhrn: 2 places in full-time study
Projekt: Genetic and epigenetic biomarkers of cancer diseases
Vedoucí: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D.
K dispozici: 3
Určeno pro: Doktorské studium
Souhrn: 3 places in full-time or combined form of study
Projekt: Identification of proteomic biomarkers in exhaled air condensate in patients with systemic or pulmonary disease
Vedoucí: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Souhrn: 2 places in full-time study
Projekt: Study of basic pharmacokinetic properties (ADME) of new drugs in preclinical development
Vedoucí: Lišková Barbora Ph.D., Hajdúch Marián M.D., Ph.D.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Antitumor drugs targeting nucleic acid metabolism
Vedoucí: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Souhrn: 2 places in full-time study
Projekt: Drug repurposing for the treatment and prevention of diseases
Vedoucí: Hajdúch Marián M.D., Ph.D., Dömling Alexander PhD.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Bioinformatics processing of big data within clinical and preclinical studies
Vedoucí: Hajdúch Marián M.D., Ph.D., Pavliš Petr Ph.D.
K dispozici: 3
Určeno pro: Doktorské studium
Souhrn: 3 places in full-time or combined form of study
Projekt: Identification of molecular targets and mechanisms of resistance in antitumor drugs
Vedoucí: Srovnal Josef M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Souhrn: 2 places in full-time study
Projekt: Identification of proteomic biomarkers in exhaled breath condensate patients with systemic or pulmonary disease
Vedoucí: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Projekt: Diagnosis and treatment of rare diseases
Vedoucí: Hajdúch Marián M.D., Ph.D., Srovnal Josef M.D., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Souhrn: 2 places in full-time study
Projekt: Genetic and epigenetic biomarkers in health and disease
Vedoucí: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D., Koudeláková Vladimíra Ph.D.
K dispozici: 5
Určeno pro: Doktorské studium
Projekt: Physiology and pathophysiology of aging
Vedoucí: Hajdúch Marián M.D., Ph.D., Voller Jiří Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Souhrn: 2 places in full-time study
Projekt: Anticancer drugs targeting nucleic acid metabolism
Vedoucí: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Projekt: Development of drugs in the field of small molecules 2 places in full-time study
Vedoucí: Dömling Alexander PhD., Hajdúch Marián M.D., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Souhrn: 2 places in full-time study
Projekt: Identification of proteomic biomarkers in proximal fluids and tissues
Vedoucí: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Projekt: Biologically active molecules and their therapeutic combinations
Vedoucí: Hajdúch Marián M.D., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Projekt: Research and development of agents for cancer, neurodegenerative and infectious diseases
Vedoucí: De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D.
K dispozici: 5
Určeno pro: Doktorské studium