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Hajdúch Marián M.D., Ph.D.

Journals

Pooling of samples to optimise SARS-CoV-2 detection in nasopharyngeal swabs and gargle lavage self-samples for covid-19 diagnostics and surveillance. Infectious Diseases. 2024, 1-12, ISSN: 2374-4243, PMID: 38549542.
DAS, V., J. MILLER, C. ALLADI, N. ANNADURAI, J. DE SANCTIS, L. HRUBÁ, M. HAJDÚCH
Antineoplastics for treating Alzheimer's disease and dementia: Evidence from preclinical and observational studies. Medicinal Research Reviews. 2024, ISSN: 0198-6325, PMID: 38530106,  PDF.
Novel triterpenoid pyrones, phthalimides and phthalates are selectively cytotoxic in CCRF-CEM cancer cells - Synthesis, potency, and mitochondrial mechanism of action. European Journal of Medicinal Chemistry. 2024, 269, 116336, ISSN: 0223-5234, PMID: 38520761,  PDF.

Intellectual property

CAFFEINE-8-HYDRAZONES AS NOVEL CYTOSTATICS FOR THE TREATMENT OF ONCOLOGIC DISEASES (Kaplánek)
  1. Patent: CZ 305625. Granted: 2.12.2015. Ownership: Institute of Chemical Technology Prague, Palacký University Olomouc, Institute of Molecular Genetics CAS. Inventors: KAPLÁNEK Robert, JAKUBEK Milan, HAVLÍK  Martin, RAK, BŘÍZA Tomáš, DŽUBÁK PetrHAJDÚCH Marián, KONEČNÝ Petr, ŠTĚPÁNKOVÁ Jana, KRÁLOVÁ Jarmila, KRÁL Vladimír 

Status: Terminated 

CHOLYL HYDRAZONES AND THEIR USE IN THE TREATMENT OF TUMOR AND LEUKEMIA DISEASES (Rak)
  1. Patent: CZ 305607. Granted: 25.11.2015. Ownership: Institute of Chemical Technology Prague, Palacký University Olomouc, Institute of Molecular Genetics CAS. Inventors: RAK Jakub, KAPLÁNEK Robert, ŠTULCOVÁ Tereza, DRAŠAR Pavel, HAVLÍK Martin, BŘÍZA Tomáš, DŽUBÁK PetrHAJDÚCH Marián, KONEČNÝ Petr, ŠTĚPÁNKOVÁ Jana, KRÁLOVÁ Jarmila, KRÁL Vladimír

Status: Terminated

METHOD OF PREDICTING THE TUMOR RESPONSE TO DNA METHYLATION INHIBITORS AND ALTERNATIVE THERAPEUTIC REGIMENS FOR OVERCOMING RESISTANCE (Khushboo)
  1. Patent: EP 2924125 (ASH1L). Granted: 17.6.2017. Ownership: Palacký University Olomouc. Inventors: AGRAWAL Khushboo, FRYDRYCH Ivo, DŽUBÁK PetrHAJDÚCH Marián
  2. Patent: EP 3042650 (JQ1). Granted: 10.6.2020. Ownership: Palacký University Olomouc. Inventors: AGRAWAL Khushboo, FRYDRYCH Ivo, DŽUBÁK PetrHAJDÚCH Marián
  3. Published Application PCT/CZ2015/000029 under WO 2015/144102 (1.10.2015)
  4. Patent: EP 3122902 (BRD4). Granted: 16.5.2018. Ownership: Palacký University Olomouc. Inventors: AGRAWAL Khushboo, FRYDRYCH Ivo, DŽUBÁK PetrHAJDÚCH Marián
  5. Published Application US 15/128,390 under US 20180251847 (6.9.2018)
  6. Patent: JP 6463372 (BRD4). Granted: 11.1.2019. Ownership: Palacký University Olomouc. Inventors: AGRAWAL Khushboo, FRYDRYCH Ivo, DŽUBÁK PetrHAJDÚCH Marián

​Status: Terminated 

Open positions

Projekt: Identification of molecular targets and mechanisms of drug resistance by cellular methods biology and proteomics
Vedoucí: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Souhrn: 2 places in full-time study
Projekt: Research and development of small-molecule drugs
Vedoucí: Hajdúch Marián M.D., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Souhrn: 2 full-time positions
Projekt: Identification of proteomic biomarkers in exhaled air condensate in patients with systemic or pulmonary disease
Vedoucí: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Souhrn: 2 places in full-time study
Projekt: Genetic and epigenetic biomarkers of cancer diseases
Vedoucí: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D.
K dispozici: 3
Určeno pro: Doktorské studium
Souhrn: 3 places in full-time or combined form of study
Projekt: Antitumor drugs targeting nucleic acid metabolism
Vedoucí: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Souhrn: 2 places in full-time study
Projekt: Drug repurposing for the treatment and prevention of diseases
Vedoucí: Hajdúch Marián M.D., Ph.D., Dömling Alexander PhD.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Study of basic pharmacokinetic properties (ADME) of new drugs in preclinical development
Vedoucí: Lišková Barbora Ph.D., Hajdúch Marián M.D., Ph.D.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 place in full-time study
Projekt: Bioinformatics processing of big data within clinical and preclinical studies
Vedoucí: Hajdúch Marián M.D., Ph.D., Pavliš Petr Ph.D.
K dispozici: 3
Určeno pro: Doktorské studium
Souhrn: 3 places in full-time or combined form of study
Projekt: Development of drugs in the field of small molecules 2 places in full-time study
Vedoucí: Dömling Alexander PhD., Hajdúch Marián M.D., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Souhrn: 2 places in full-time study
Projekt: Diagnosis and treatment of rare diseases
Vedoucí: Hajdúch Marián M.D., Ph.D., Srovnal Josef M.D., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Souhrn: 2 places in full-time study
Projekt: Identification of new derivatives targeting precancerous and tumor lesions and their mechanisms of action
Vedoucí: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Souhrn: 2 full-time positions
Projekt: New diagnostic, prognostic, and predictive factors in solid tumors
Vedoucí: Hajdúch Marián M.D., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Souhrn: 2 positions (full-time or part-time)
Projekt: Identification of molecular targets and mechanisms of resistance in anticancer drugs using cell biology and proteomics
Vedoucí: Hajdúch Marián M.D., Ph.D.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 full-time position
Projekt: Anticancer drugs targeting nucleic acid metabolism
Vedoucí: Hajdúch Marián M.D., Ph.D.
K dispozici: 1
Určeno pro: Doktorské studium
Souhrn: 1 full-time position
Projekt: Bioinformatics processing of large datasets in clinical and preclinical studies
Vedoucí: Hajdúch Marián M.D., Ph.D., Pavliš Petr Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Souhrn: 2 positions (full-time or part-time)
Projekt: Anticancer drugs targeting nucleic acid metabolism
Vedoucí: Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Projekt: Diagnosis and treatment of rare diseases
Vedoucí: Hajdúch Marián M.D., Ph.D., Srovnal Josef M.D., Ph.D., Adam Tomáš Ph.D.
K dispozici: 3
Určeno pro: Doktorské studium
Souhrn: 3 full-time positions
Projekt: Genetic and epigenetic biomarkers in health and disease
Vedoucí: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D., Koudeláková Vladimíra Ph.D.
K dispozici: 5
Určeno pro: Doktorské studium
Projekt: Identification of proteomic biomarkers in exhaled breath condensate patients with systemic or pulmonary disease
Vedoucí: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Projekt: Biologically active molecules and their therapeutic combinations
Vedoucí: Hajdúch Marián M.D., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Projekt: Identification of proteomic biomarkers in proximal fluids and tissues
Vedoucí: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Projekt: Research and development of agents for cancer, neurodegenerative and infectious diseases
Vedoucí: De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D.
K dispozici: 5
Určeno pro: Doktorské studium
Projekt: Identification of molecular targets and mechanisms of resistance in antitumor drugs
Vedoucí: Srovnal Josef M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Souhrn: 2 places in full-time study
Projekt: Physiology and pathophysiology of aging
Vedoucí: Hajdúch Marián M.D., Ph.D., Voller Jiří Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Souhrn: 2 places in full-time study