Header image
Džubák Petr M.D., Ph.D.
E-mail:
petr.dzubak@upol.cz
Telefon:
+420 585632150, +420 604851158
Skupiny:
ÚMTM, LEM, PERSONÁL, VEDOUCÍ
O mně
Scientist and pediatrician involved in molecular and translational medicine (disease area oncology and infectious diseases), leader of research program Chemical Biology and Experimental Therapeutics at IMTM. Actively participated in the research of more than 20 national and international projects; member of advisory board of Cancer Research Foundation „Rakovina ve veřejná“, co-founder of spin-off company focused on manufacturing of molecular diagnostics. Published more than >140 papers and books/chapters, >3552 SCI citations, H-index 27, Prix de Pharmacie 2007 Ambassade de France – Sanofi-aventis, Premier Prix.
Specialties: Molecular and translational medicine, Oncology, Drug research and development, MOA, Drug resistance
Journals
Synthesis and evaluation of cyclobut-3-ene-1,2-dione-3-hydrazones with benzothiazole moiety as novel anticancer agents inducing nonapoptotic oncosis-like cell death.
Biomedicine & pharmacotherapy.
2025,
ISSN: 0753-3322,
PMID: 40763487,
Books & book chapters
Detekce nádorových biomarkerů v molekulárně biologické laboratoři,
1. vyd,
Olomouc,
Univerzita Palackého v Olomouci,
2012,
144 s,
Dedication: MOLONKOL CZ.1.07/2.3.00/09.0089,
ISBN: 978-80-244-3002-7,
The Potential of Triterpenoids in the Treatment of Melanoma,
1.vyd,
Rijeka,
InTech,
2011,
7,
125-158,
Dedication: 305/09/1216,
ISBN: 978-953-307-293-7,
Intellectual property
BIOAVAILABLE DITHIOCARBAMATE-METAL COMPLEX NANOPARTICLES, METHOD OF PREPARATION AND USE THEREOF - EP 17193240.3 (Škrott) DISULFIRAM I
- Patent: EP 3459526. Granted: 24.2.2021. Ownership: Palacký University Olomouc. Inventors: Škrott Zdeněk, Mistrík Martin, Hajdúch Marián, Bártek Jiří, Džubák Petr, Zbořil Radek.
- Published Application: PCT/EP2018/076098 under WO 2019/063601 (4.4.2019)
- Patent: US 11,766,404. Granted: 26.9.2023. Ownership: Palacký University Olomouc. Inventors: Škrott Zdeněk, Mistrík Martin, Hajdúch Marián, Bártek Jiří, Džubák Petr, Zbořil Radek.
- Patent: AU 2018340510. Granted: 5.8.2021. Ownership: Palacký University Olomouc. Inventors: Škrott Zdeněk, Mistrík Martin, Hajdúch Marián, Bártek Jiří, Džubák Petr, Zbořil Radek.
- Patent: IL 273652. Granted: 2.1.2024. Ownership: Palacký University Olomouc. Inventors: Škrott Zdeněk, Mistrík Martin, Hajdúch Marián, Bártek Jiří, Džubák Petr, Zbořil Radek.
- Patent: CA 3,076,855. Granted: 26.4.2022. Ownership: Palacký University Olomouc. Inventors: Škrott Zdeněk, Mistrík Martin, Hajdúch Marián, Bártek Jiří, Džubák Petr, Zbořil Radek.
- Patent: KR 10-2456683. Granted: 14.10.2022. Ownership: Palacký University Olomouc. Inventors: Škrott Zdeněk, Mistrík Martin, Hajdúch Marián, Bártek Jiří, Džubák Petr, Zbořil Radek.
- Patent: JP 7149624. Granted: 29.9.2022. Ownership: Palacký University Olomouc. Inventors: Škrott Zdeněk, Mistrík Martin, Hajdúch Marián, Bártek Jiří, Džubák Petr, Zbořil Radek.
- Patent: MX 396,552. Granted: 17.10.2022. Ownership: Palacký University Olomouc. Inventors: Škrott Zdeněk, Mistrík Martin, Hajdúch Marián, Bártek Jiří, Džubák Petr, Zbořil Radek.
- Patent: BR 112020005823-8. Granted: 12.11.2024. Ownership: Palacký University Olomouc. Inventors: Škrott Zdeněk, Mistrík Martin, Hajdúch Marián, Bártek Jiří, Džubák Petr, Zbořil Radek.
Status: Available
SUBSTITUTED HETEROPENTADIENO-PYRROLOPYRIMIDINE RIBONUCLEOSIDES FOR THERAPEUTIC USE - PV 2014-465 (Hocek)
Patent: US 10,730,905. Granted: 4.8.2020. Ownership: Institute of Organic Chemistry and Biochemistry CAS; Palacký University Olomouc. Inventors: HOCEK Michal, TOKARENKO Anna, SMOLEŇ Sabina, DŽUBÁK Petr, HAJDÚCH Marián
Status: Available
NOVEL SUBSTITUTED 7-DEAZAPURINE RIBONUCLEOSIDES FOR THERAPEUTIC USES - PV 2013-845 (Hocek)
- Patent: CZ 305466. Granted: 7.9.2015. Ownership: Institute of Organic Chemistry and Biochemistry CAS; Palacký University Olomouc. Inventors: HOCEK Michal, NAUŠ Petr, CALETKOVÁ Olga, DŽUBÁK Petr, HAJDÚCH Marián
- Patent: JP 5485172. Granted: 7.5.2014. Ownership: Institute of Organic Chemistry and Biochemistry CAS; Palacký University Olomouc. Inventors: HOCEK Michal, NAUŠ Petr, CALETKOVÁ Olga, DŽUBÁK Petr, HAJDÚCH Marián
- Patent: US 9,586,986. Granted: 7.3.2017. Ownership: Institute of Organic Chemistry and Biochemistry CAS; Palacký University Olomouc. Inventors: HOCEK Michal, NAUŠ Petr, CALETKOVÁ Olga, DŽUBÁK Petr, HAJDÚCH Marián
Patent: AU 2014277740. Granted: 25.2.2016. Ownership: Institute of Organic Chemistry and Biochemistry CAS; Palacký University Olomouc. Inventors: HOCEK Michal, NAUŠ Petr, CALETKOVÁ Olga, DŽUBÁK Petr, HAJDÚCH Marián
Status: Not available.
Doctoral mentorship
Holub Dušan Ph.D.
Development of a method for the sensitive and quantitative determination of hepcidin in human serum using LCMS
Stav:
Absolvoval od 2009 do 2016.
Václavková Jana Ph.D.
Identification of mechanisms of action of molecules with anticancer effect
Stav:
Absolvoval od 2014 do 2021.
Hrubá Lenka RNDr., Ph.D.
Mechanism of multidrug resistance (MDR) in cancer cells
Stav:
Absolvoval od 2015 do 2023.
Open positions
| Projekt: | Identification of molecular targets and mechanisms of drug resistance by cellular methods biology and proteomics |
|---|---|
| Vedoucí: | Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D. |
| K dispozici: | 2 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 2 places in full-time study |
| Projekt: | Utilization of the space of unprecedented covalent inhibitors |
|---|---|
| Vedoucí: | Dömling Alexander PhD., Džubák Petr M.D., Ph.D. |
| K dispozici: | 1 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 1 place in full-time study |
| Projekt: | Identification of molecular targets of antitumor drugs using methods of cell biology and proteomics |
|---|---|
| Vedoucí: | Džubák Petr M.D., Ph.D. |
| K dispozici: | 2 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 2 places in full-time study |
| Projekt: | Identification of proteomic biomarkers in exhaled air condensate in patients with systemic or pulmonary disease |
|---|---|
| Vedoucí: | Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D. |
| K dispozici: | 2 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 2 places in full-time study |
| Projekt: | Genetic and epigenetic biomarkers of cancer diseases |
|---|---|
| Vedoucí: | Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D. |
| K dispozici: | 3 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 3 places in full-time or combined form of study |
| Projekt: | Identification of proteomic biomarkers in tears of patients with brain cancer |
|---|---|
| Vedoucí: | Džubák Petr M.D., Ph.D. |
| K dispozici: | 1 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 1 place in full-time study |
| Projekt: | Identification of proteomic biomarkers in tears of patients with neurodegenerative diseases |
|---|---|
| Vedoucí: | Džubák Petr M.D., Ph.D. |
| K dispozici: | 1 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 1 place in full-time study |
| Projekt: | Antitumor drugs targeting nucleic acid metabolism |
|---|---|
| Vedoucí: | Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D. |
| K dispozici: | 2 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 2 places in full-time study |
| Projekt: | Synthesis of kinase inhibitors and their phenotypic chemoproteomic evaluation |
|---|---|
| Vedoucí: | Dömling Alexander PhD., Džubák Petr M.D., Ph.D. |
| K dispozici: | 1 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 1 place in full-time study |
| Projekt: | Targeted approaches to covalent inhibitors |
|---|---|
| Vedoucí: | Dömling Alexander PhD., Džubák Petr M.D., Ph.D. |
| K dispozici: | 1 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 1 place in full-time study |
| Projekt: | Identification of new derivatives targeting precancerous and tumor lesions and their mechanisms of action |
|---|---|
| Vedoucí: | Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D. |
| K dispozici: | 2 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 2 full-time positions |
| Projekt: | Genetic and epigenetic biomarkers in health and disease |
|---|---|
| Vedoucí: | Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D., Koudeláková Vladimíra Ph.D. |
| K dispozici: | 5 |
| Určeno pro: | Doktorské studium |
| Projekt: | Identification of proteomic biomarkers in exhaled breath condensate patients with systemic or pulmonary disease |
|---|---|
| Vedoucí: | Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D. |
| K dispozici: | 2 |
| Určeno pro: | Doktorské studium |
| Projekt: | Identification of proteomic biomarkers in proximal fluids and tissues |
|---|---|
| Vedoucí: | Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D. |
| K dispozici: | 2 |
| Určeno pro: | Doktorské studium |
| Projekt: | Research and development of agents for cancer, neurodegenerative and infectious diseases |
|---|---|
| Vedoucí: | De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D. |
| K dispozici: | 5 |
| Určeno pro: | Doktorské studium |
| Projekt: | Omic approaches in reproductive medicine |
|---|---|
| Vedoucí: | Džubák Petr M.D., Ph.D., Oždian Tomáš Ph.D. |
| K dispozici: | 1 |
| Určeno pro: | Doktorské studium |
| Souhrn: | 1 place in full-time study |
| Projekt: | Anticancer drugs targeting nucleic acid metabolism |
|---|---|
| Vedoucí: | Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D. |
| K dispozici: | 2 |
| Určeno pro: | Doktorské studium |