Urban Milan Ph.D.

Journals

BORKOVÁ, L., I. FRYDRYCH, B. VRÁNOVÁ, N. JAKUBCOVÁ, B. LIŠKOVÁ, P. DŽUBÁK, P. PAVLIŠ, M. HAJDÚCH, M. URBAN
Lupane derivatives containing various aryl substituents in the position 3 have selective cytostatic effect in leukemic cancer cells including resistant phenotypes. European Journal of Medicinal Chemistry. 2022, 244, 114850, ISSN: 0223-5234, PMID: 36283179,
HODOŇ, J., I. FRYDRYCH, Z. TRHLÍKOVÁ, J. POKORNÝ, L. BORKOVÁ, S. BENICKÁ, M. VLK, B. LIŠKOVÁ, A. KUBÍČKOVÁ, M. MEDVEDÍKOVÁ, M. PISÁR, J. ŠAREK, V. DAS, A. LIGASOVÁ, K. KOBERNA, P. DŽUBÁK, M. HAJDÚCH, M. URBAN
Triterpenoid pyrazines and pyridines - Synthesis, cytotoxicity, mechanism of action, preparation of prodrugs. European Journal of Medicinal Chemistry. 2022, 243, 114777, ISSN: 0223-5234, PMID: 36174412,  PDF.
POKORNÝ, J., D. OLEJNÍKOVÁ, I. FRYDRYCH, B. LIŠKOVÁ, S. GURSKÁ, S. BENICKÁ, J. ŠAREK, J. KOTULOVÁ, M. HAJDÚCH, P. DŽUBÁK, M. URBAN
Substituted dienes prepared from betulinic acid - Synthesis, cytotoxicity, mechanism of action, and pharmacological parameters. European Journal of Medicinal Chemistry. 2021, 224, 113706, ISSN: 0223-5234, PMID: 34311159,

Doctoral mentorship

Šťastná Barbora

Modification of pentacyclic triterpene molecules in the E and A ring regions and study of their antitumor activity

Stav: Probíhající od 2025.

Master mentorship

Orság Šimon

Preparation of new heterocyclic derivatives of triterpene

Stav: Absolvoval od 2020 do 2022.
Jurčeka Ondřej

Triterpenes modified at the position 30

Stav: Absolvoval od 2020 do 2022.
Borková Lucie Ph.D.

Modification of the position 2 in betulin, allobetulin and betulinic acid with polar substituents

Stav: Absolvoval od 2012 do 2014.

Bachelor mentorship

Trhlíková Zdeňka

Preparation of heterocyclic triterpenes

Stav: Absolvoval od 2013 do 2017.
Jurčeka Ondřej

Triterpenes modified at the position 30

Stav: Absolvoval od 2018 do 2020.
Hodoň Jiří, Ph.D.

Attempt to find the mechanism of action in cytotoxic active triterpenes

Stav: Absolvoval od 2012 do 2015.

Open positions

Projekt: Natural compounds with anti tumor activity
Vedoucí: Urban Milan Ph.D.
K dispozici: 2
Určeno pro: Doktorské studium
Souhrn: 2 full-time positions
Projekt: Research and development of agents for cancer, neurodegenerative and infectious diseases
Vedoucí: De Sanctis Juan Bautista Ph.D., Hajdúch Marián M.D., Ph.D., Džubák Petr M.D., Ph.D., Urban Milan Ph.D., Das Viswanath M.Sc., Ph.D.
K dispozici: 5
Určeno pro: Doktorské studium