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Adámek Richard
E-mail:
richard.adamek02@upol.cz
Groups:
BACHELOR STUDENT
Bachelor training
Modification of triterpenes with the use of selected transition metal catalyzed reactions
The main aim is to prepare a small set of new triterpenoid derivatives using transition metal catalyzed crosscouplings of triterpenes with small molecules. The reaction conditions must be found and then, the new derivatives will be studied for their cytotoxic activity.
Supervisor:
Borková Lucie Ph.D.
Status:
Graduated from 2013 to 2016.
Journals
Synthesis and biological evaluation of triterpenoid thiazoles derived from betulonic acid, dihydrobetulonic acid, and ursonic acid.
European Journal of Medicinal Chemistry.
2019,
185,
111806,
ISSN: 0223-5234,
PMID: 31677446,
Synthesis and Cytotoxic Activity of Triterpenoid Thiazoles Derived from Allobetulin, Methyl Betulonate, Methyl Oleanonate, and Oleanonic Acid.
ChemMedChem.
2017,
12(5),
390-398,
ISSN: 1860-7179,
PMID: 28084676,