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Moudrý Pavel Ph.D.
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About me
Head of the DNA Replication Dynamics research group at the Institute of Molecular and Translational Medicine.
Researcher with extensive expertise in DNA replication and the DNA damage response.
Author of 18 scientific publications, with more than 2300 citations and an h-index of 16.
Evaluator for national and international grant competitions and research assessment.
Reviewer for international peer-reviewed scientific journals.
Supervisor and mentor of Bachelor’s, Master’s, and PhD students.
Positions are available for motivated Master’s and PhD students interested in DNA replication and clinically relevant research aimed at improving PARP inhibitor therapy. Please contact me for further information.
Journals
High speed of fork progression induces DNA replication stress and genomic instability.
Nature.
2018,
559(7713),
279-284,
ISSN: 0028-0836,
PMID: 29950726,
Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4.
Nature.
2017,
552(7684),
194-199,
ISSN: 0028-0836,
PMID: 29211715,
Perturbation of RNA Polymerase I transcription machinery by ablation of HEATR1 triggers the RPL5/RPL11-MDM2-p53 ribosome biogenesis stress checkpoint pathway in human cells.
Cell Cycle.
2017,
17(1),
92-101,
ISSN: 1538-4101,
PMID: 29143558,
Open positions
| Project: | Cellular stress in health and disease |
|---|---|
| Supervisors: | Mistrík Martin Ph.D., Moudrý Pavel Ph.D., Škrott Zdeněk Ph.D. |
| Available: | 3 |
| Intended for: | Doctoral training |
| Project: | DNA replication in human pathophysiology |
|---|---|
| Supervisors: | Moudrý Pavel Ph.D. |
| Available: | 1 |
| Intended for: | Doctoral training |
| Summary: | 1 full-time position |