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Lukáč Dávid MSc
Doctoral training
DNA replication and cancer
Specialization:
Medical genetics
Supervisor:
Moudrý Pavel Ph.D.
Status:
Graduated from 2020 to 2025.
About me
PhD student in the 4th year of study, and a member of the DNA Replication Dynamics group. Specializing in the DNA replication machinery in cancer cell lines, with a focus on replication stress and replication stress responses caused by PARP inhibitors (PARPi). We investigate these processes using various approaches, including advanced laser microscopy methods, cell cultures, and immunoblotting.
Journals
Emetine blocks DNA replication via proteosynthesis inhibition not by targeting Okazaki fragments.
Life Science Alliance.
2022,
5(12),
e202201560,
ISSN: 2575-1077,
PMID: 36260751,
Cannabidiol-induced activation of the metallothionein pathway impedes anticancer effects of disulfiram and its metabolite CuET.
Molecular Oncology.
2021,
16(7),
1541-1554,
ISSN: 1574-7891,
PMID: 34632694,