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Najdekr Lukáš Ph.D.

Journals

BEGER, R., R. GOODACRE, C. JONES, K. LIPPA, O. MAYBORODA, D. O´NEILL, L. NAJDEKR, I. NTAI, I. WILSON, W. DUNN
Analysis types and quantification methods applied in UHPLC-MS metabolomics research: a tutorial. Metabolomics. 2024, 20(5), 95, ISSN: 1573-3882, PMID: 39110307,  PDF.
NASH, W., J. NGERE, L. NAJDEKR, W. DUNN
Characterization of Electrospray Ionization Complexity in Untargeted Metabolomic Studies. Analytical Chemistry. 2024, ISSN: 0003-2700, PMID: 38917347.  PDF.
KVASNIČKA, A., L. NAJDEKR, D. DOBEŠOVÁ, B. PISKLÁKOVÁ, E. IVANOVOVÁ, D. FRIEDECKÝ
Clinical lipidomics in the era of the big data. Clinical Chemistry and Laboratory Medicine. 2023, 61(4), 587-598, ISSN: 1434-6621, PMID: 36592414,  PDF.

Doctoral mentorship

Macháň Jan

Application of open-source software approaches for analyses of clinical metabolmics and lipidomics data

Status: Ongoing from 2023.
Masař Richard

Lipidomic and proteomic biomarkers of cancer

Status: Ongoing from 2024.

Master mentorship

Mádrová Lucie M.Sc

Usage of lipid profile for study of inherited metabolic disorders

Status: Graduated from 2013 to 2015.
Filipová Sára

Metabolomic characterisation of endometriosis

Status: Ongoing from 2023.
Masař Richard

Lipidomic profiling of cardiovascular disease

Status: Graduated from 2021 to 2024.

Bachelor mentorship

Boyko Daniel

Targeted metabolomics of transgenic mice suffering from LPS-induced neuroinflammation

Status: Graduated from 2017 to 2018.
Filipová Sára

Analysis of omega-3 fatty acid from fish extracts

Status: Graduated from 2021 to 2023.
Masař Richard

Development and validation of LC/MS assay for analyses of fat-soluble vitamins

Status: Graduated from 2021 to 2022.

Open positions

Project: Application of untargeted lipidomics and metabolomics as a tool for generating hypotheses in personalized medicine
Supervisors: Najdekr Lukáš Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Applied lipidomics approach in the search for new clinical biomarkers and elucidation of the structure of unknown lipid species
Supervisors: Najdekr Lukáš Ph.D.
Available: 1
Intended for: Doctoral training
Summary: 1 place in full-time study
Project: Use of open-source software approaches for analysis of metabolomic and lipidomic clinical data
Supervisors: Najdekr Lukáš Ph.D.
Available: 1
Intended for: Doctoral training
Project: Isolation and analysis of membrane lipid rafts using a non-targeted metabolomics and lipidomics approach
Supervisors: Najdekr Lukáš Ph.D.
Available: 1
Intended for: Doctoral training
Project: Vitamin analysis in human plasma cohort by application of UHPLC-MS
Supervisors: Najdekr Lukáš Ph.D.
Available: 1
Intended for: Bachelor training
Summary: Description: The main goal would be to learn basic analytical skills in the metabolomics laboratory. Starting with sample preparation (different types of extractions), followed by data acquisition on the LCMS analytical platform. The last step is a biological interpretation of measured data; in this case, the effects of vitamin deficiency or overdose on the human organism.